Level-Dependent Coronal and Axial Moment-Rotation Corridors of Degeneration-Free Cervical Spines in Lateral Flexion

Yoganandan, Narayan; Pintar, Frank A.; Stemper, Brian D.; Wolfla, Christopher E.; Shender, Barry S.; Paskoff, Glenn
May 2007
Journal of Bone & Joint Surgery, American Volume;May2007, Vol. 89-A Issue 5, p1066
Academic Journal
Background: Aging, trauma, or degeneration can affect intervertebral kinematics. While in vivo studies can determine motions, moments are not easily quantified. Previous in vitro studies on the cervical spine have largely used specimens from older individuals with varying levels of degeneration and have shown that moment-rotation responses under lateral bending do not vary significantly by spinal level. The objective of the present in vitro biomechanical study was, therefore, to determine the coronal and axial moment-rotation responses of degeneration-free, normal, intact human cadaveric cervicothoracic spinal columns under the lateral bending mode. Methods: Nine human cadaveric cervical columns from C2 to T1 were fixed at both ends. The donors had ranged from twenty-three to forty-four years old (mean, thirty-four years) at the time of death. Retroreflective targets were inserted into each vertebra to obtain rotational kinematics in the coronal and axial planes. The specimens were subjected to pure lateral bending moment with use of established techniques. The range-of-motion and neutral zone metrics for the coronal and axial rotation components were determined at each level of the spinal column and were evaluated statistically. Results: Statistical analysis indicated that the two metrics were level-dependent (p < 0.05). Coronal motions were significantly greater (p < 0.05) than axial motions. Moment-rotation responses were nonlinear for both coronal and axial rotation components under lateral bending moments. Each segmental curve for both rotation components was well represented by a logarithmic function (R² > 0.95). Conclusions: Range-of-motion metrics compared favorably with those of in vivo investigations. Coronal and axial motions of degeneration-free cervical spinal columns under lateral bending showed substantially different level-dependent responses. The presentation of moment-rotation corridors for both metrics forms a normative dataset for the degeneration-free cervical spines. Clinical Relevance: While clinical studies provide some information on spinal motions, laboratory-driven experimental biomechanical studies allow controlled load application, document motion magnitudes, and provide a critical dataset of moment-rotation responses. Because these data are derived from degeneration-free spines, validation efforts with use of this dataset will greatly improve model predictabilities while studying the effects of pathological processes, trauma, or instrumentation on spinal kinetics and, hence, stability.


Related Articles

  • Intraoperative determination of the load-displacement behavior of scoliotic spinal motion segments: preliminary clinical results. Reutlinger, Christoph; Hasler, Carol; Scheffler, Klaus; Büchler, Philippe // European Spine Journal;Aug2012 Supplement, Vol. 21, p860 

    Introduction: Spinal fusion is a widely and successfully performed strategy for the treatment of spinal deformities and degenerative diseases. The general approach has been to stabilize the spine with implants so that a solid bony fusion between the vertebrae can develop. However, new implant...

  • Minimally invasive spine stabilisation with long implants. Logroscino, Carlo Ambrogio; Proietti, Luca; Tamburrelli, Francesco Ciro // European Spine Journal;Jun2009 Supplement 1, Vol. 18, p75 

    Originally aimed at treating degenerative syndromes of the lumbar spine, percutaneous minimally invasive posterior fixation is nowadays even more frequently used to treat some thoracolumbar fractures. According to the modern principles of saving segment of motion, a short implant (one level...

  • Anterior cervical fusion with polyetheretherketone (PEEK) cages in the treatment of degenerative disc disease. Preliminary observations in 36 consecutive cases with a minimum 12-month follow-up. Mastronardi, L.; Ducati, A.; Ferrante, L. // Acta Neurochirurgica;Mar2006, Vol. 148 Issue 3, p307 

    Study design. Retrospective analysis of 36 cases of degenerative disc disease treated by interbody fusion with polyetheretherketone (PEEK) cages. Objective. To determine the safety and efficiency of PEEK cages for anterior cervical fusion (ACF). Summary of background data. ACF with autologous...

  • Standortbestimmung der lumbalen Bandscheibenendoprothetik. Zarghooni, K.; Siewe, J.; Eysel, P. // Der Orthopäde;Feb2011, Vol. 40 Issue 2, p141 

    Lumbar intervertebral total disc replacement is becoming more commonly employed for patients with degenerative disc disease as an alternative to spinal arthrodesis. Postulated advantages for the patients are motion preservation and height restoration in the affected segment, preventing adjacent...

  • FOR BACK PAIN, A NEW KIND OF COMPACT DISC.  // Time;11/8/2004, Vol. 164 Issue 19, p109 

    Reports that the Food and Drug Administration approved an artificial disk called the Charité to treat Americans with chronic lower back pain. How the disk is designed to replace the natural fluid-filled disks of the lower spine when they are damaged by degenerative disk disease; Findings...

  • Assessing the use of artificial cervical disc implants in treating cervical spondylosis. Fox, Sally; Choi, David // British Journal of Neuroscience Nursing;Jul2009, Vol. 5 Issue 7, p319 

    Cervical spondylosis often affects people over 50 years of age. It is due to degenerative changes in the discs and facets joints which may impinge on the spinal cord, causing neurological symptoms and pain. Treatment may involve physiotherapy, analgesia, injection treatments or surgery to remove...

  • Posterior lumbar interbody fusion using rhBMP-2. Meisel, Hans Jürg; Schnöring, Mark; Hohaus, Christian; Minkus, Yvonne; Beier, Andre; Ganey, Timothy; Mansmann, Ulrich // European Spine Journal;Dec2008, Vol. 17 Issue 12, p1735 

    The use of biological technologies for the treatment of degenerative spinal diseases has undergone rapid clinical and scientific development. BMP strategies have gained wide support for an inherent potential to improve the ossification process. It has been extensively studied in combination with...

  • The differently expressed proteins in MSCs of degenerative scoliosis. Han, Shijie; Zhu, Yong; Wu, Zhihong; Zhang, Jianguo; Qiu, Guixing // Journal of Orthopaedic Science;Nov2013, Vol. 18 Issue 6, p885 

    Purpose: Degenerative scoliosis (DS) is an important degenerative lumbar disease causing spinal dysfunction. The true reason or pathogenesis of DS is still unknown. Bone marrow-derived mesenchymal stem cells (BM-MSCs) are the stem/progenitor cells of the osteoblasts. The diseases associated with...

  • Kienböck's disease.  // Taber's Cyclopedic Medical Dictionary (2009);2009, Issue 21, p1269 

    A reference entry for "Kienböck's disease" which refers to the slow degeneration of the lunate bone of the wrist is presented.


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics