TITLE

Effect of Tilarginine Acetate in Patients With Acute Myocardial Infarction and Cardiogenic Shock

PUB. DATE
April 2007
SOURCE
JAMA: Journal of the American Medical Association;4/18/2007, Vol. 297 Issue 15, p1657
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
The article presents a randomized controlled trial that examined the effects of the nitric oxide synthase inhibitor tilarginine acetate in patients with myocardial infarction and refractory cardiogenic shock. All patients in the study had an open infarct artery. Outcomes measured in the study included mortality from any cause, resolution and duration of shock, and the duration of mechanical ventilation and intra-aortic balloon pump support. The study found that tilarginine did not reduce mortality rates in patients with refractory cardiogenic shock and myocardial infarction.
ACCESSION #
24798048

 

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