TITLE

Blood pressure in head-injured patients

AUTHOR(S)
Mitchell, Patrick; Gregson, Barbara A.; Piper, Ian; Citerio, Giuseppe; Mendelow, A. David; Chambers, Iain R.
PUB. DATE
April 2007
SOURCE
Journal of Neurology, Neurosurgery & Psychiatry;Apr2007, Vol. 78 Issue 4, p399
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Objective: To determine the statistical characteristics of blood pressure (BP) readings from a large number of head-injured patients. Methods: The BrainlT group has collected high time-resolution physiological and clinical data from head-injured patients who require intracranial pressure (ICP) monitoring. The statistical features of this dataset of BP measurements with time resolution of 1 min from 200 patients is examined. The distributions of BP measurements and their relationship with simultaneous ICP measurements are described. Results: The distributions of mean, systolic and diastolic readings are close to normal with modest skewing towards higher values. There is a trend towards an increase in blood pressure with advancing age, but this is not significant. Simultaneous blood pressure and ICP values suggest a triphasic relationship with a BP rising at 0.28 mm Hg/mm Hg of ICP, for ICP up to 32 mm Hg, and 0.9 mm Hg/mm Hg of ICP for ICP from 33 to 55 mm Hg, and falling sharply with rising ICP for ICP >55 mm Hg. Conclusions: Patients with head injury appear to have a near normal distribution of blood pressure readings that are skewed towards higher values. The relationship between BP and ICP may be triphasic.
ACCESSION #
24777689

 

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