Huibregtse, I. L.; Van Lent, A. U.; Van Deventer, S. J. H.
April 2007
Gut;Apr2007, Vol. 56 Issue 4, p584
Academic Journal
The article offers insights into evidence for abnormal regulation of T cell activation in Crohn's disease, as well as data concerning the existence and functional activity of regulatory T cells in the intestinal mucosa. Regulatory T cells have important functions in suppressing unwanted inflammatory responses towards self antigens and the antigens of endogenous intestinal bacteria. The article also considers the potential therapeutic application of Treg in inflammatory bowel diseases.


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