TITLE

MESENTERIC FAT IN CROHN'S DISEASE: A PATHOGENETIC HALLMARK OR AN INNOCENT BYSTANDER?

AUTHOR(S)
Peyrin-Biroulet, Laurent; Chamaillard, Mathias; Gonzalez, Florent; Beclin, Elodie; Decourcelle, Cecilia; Antunes, Laurent; Gay, Jérôme; Neut, Christel; Colombel, Jean-Frédéric; Desreumaux, Pierre
PUB. DATE
April 2007
SOURCE
Gut;Apr2007, Vol. 56 Issue 4, p577
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
The article discusses the normal and pathophysiological functions of mesenteric white adipose tissue (WAT). WAT may play an important role in the inflammatory and fibrotic processes in Crohn's disease, a frequent and complex form of inflammatory bowel disease. The mesenteric fat may contribute to the increase C-reactive protein production. Moreover, it could also influence the gut barrier function by promoting the innate immune response to the gut flora.
ACCESSION #
24767589

 

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