TITLE

In vivo single-photon emission computed tomography imaging of apoptosis in Crohn's disease and anti-tumour necrosis factor therapy

AUTHOR(S)
Watson, Alastair J. M.
PUB. DATE
April 2007
SOURCE
Gut;Apr2007, Vol. 56 Issue 4, p461
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
The article reports on a study by J. M. H. Van der Brande and colleagues on evidence for the importance of apoptosis of lamina propria T cells in the action of infliximab. The researchers demonstrate that apoptosis in the intestine is increased compared with uninflammed intestine in two mouse models of colitis. They also show that infliximab induces more apoptosis in patients with Crohn's disease who respond than those who do not respond.
ACCESSION #
24767570

 

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