Transplanting the enteric nervous system: a step closer to treatment for aganglionosis

Gershon, Michael D.
April 2007
Gut;Apr2007, Vol. 56 Issue 4, p459
Academic Journal
The article comments on a study by S. Almond and colleagues on major problems that must be overcome before enteric neural crest-derived stem cells can be successfully used to treat Hirschsprung's disease. The researchers note that the crest-derived stem cells have to be isolated and then expanded to obtain enough cells for autologous transplantation. They have adapted the technique of producing neurospheres from single-cell suspensions to obtain enriched populations of crest-derived stem cells.


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