TITLE

Metal(II) Schiff base complexes as catalysts for the high-regioselective conversion of epoxides to �-hydroxy nitriles in glycol solvents

AUTHOR(S)
Naeimi, Hossein; Moradian, Mohsen
PUB. DATE
November 2006
SOURCE
Canadian Journal of Chemistry;Nov2006, Vol. 84 Issue 11, p1575
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
A facile preparation of 3-hydroxy propanenitrile derivatives is described involving ring opening of epoxides with potassium cyanide in glycol solvents in the presence of Schiff base complexes as catalysts. This method occurs under neutral and mild conditions with high yields and high regioselectivity. Thus, several �-Hydroxy nitriles, useful intermediates toward biologically-active molecules, are easily obtained at room temperature.
ACCESSION #
24715610

 

Related Articles

Share

Read the Article

Courtesy of VIRGINIA BEACH PUBLIC LIBRARY AND SYSTEM

Sign out of this library

Other Topics