TITLE

Providing AID to p53 mutagenesis

AUTHOR(S)
Takaishi, Shigeo; Wang, Timothy C.
PUB. DATE
April 2007
SOURCE
Nature Medicine;Apr2007, Vol. 13 Issue 4, p404
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
The article discusses a study which presents a unique mechanism for p53 mutations in gastric cancer associated with Helicobacter pylori infection. The researchers found that the infection caused the aberrant expression of activation-induced cytidine deaminase, an enzyme that mediates antibody diversification.
ACCESSION #
24629911

 

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