Doe Program–Developing a Scientific Basis for Responses to Low-Dose Exposures: Impact on Dose-Response Relationships
- Transcriptional Response of Ex Vivo Human Skin to Ionizing Radiation: Comparison Between Low- and High-Dose Effects. Albrecht, Huguette; Durbin-Johnson, Blythe; Yunis, Reem; Kalanetra, Karen M.; Wu, Shiquan; Chen, Rachel; Stevenson, Thomas R.; Rocke, David M. // Radiation Research;Jan2012, Vol. 177 Issue 1, p69
Although human exposure to low-dose ionizing radiation can occur through a variety of sources, including natural, medical, occupational and accidental, the true risks of low-dose ionizing radiation are still poorly understood in humans. Here, the global transcriptional responses of human skin...
- The miR-99 family regulates the DNA damage response through its target SNF2H. Mueller, A C; Sun, D; Dutta, A // Oncogene;2/28/2013, Vol. 32 Issue 9, p1164
Chromatin remodeling factors are becoming known as crucial facilitators of recruitment of repair proteins to sites of DNA damage. Multiple chromatin remodeling protein complexes are now known to be required for efficient double strand break repair. In a screen for microRNAs (miRNAs) that...
- Radiation-induced versus endogenous DNA damage: possible effect of inducible protective responses in mitigating endogenous damage. Pollycove, Myron; Feinendegen, Ludwig E // Human & Experimental Toxicology;Jun2003, Vol. 22 Issue 6, p290
Ionizing radiation (IR) causes damage to DNA that is apparently proportional to absorbed dose. The incidence of radiation-induced cancer in humans unequivocally rises with the value of absorbed doses above about 300 mGy, in a seemingly linear fashion. Extrapolation of this linear correlation...
- Letter to the Editor: Reply to Cohen's Response to EPA Position on Cancer Risk From Low Level Radiation. Puskin, Jerome S. // Dose-Response;2010, Vol. 8 Issue 3, p387
No abstract available.
- Investigation of DNA Damage Dose-Response Kinetics after Ionizing Radiation Schemes Similar to CT Protocols. Elgart, S. Robin; Bostani, Maryam; Mok, Karen C.; Adibi, Ali; Ruehm, Stefan; Enzmann, Dieter; McNitt-Gray, Michael; Iwamoto, Keisuke S. // Radiation Research;Jun2015, Vol. 183 Issue 6, p701
Although there has been extensive research done on the biological response to doses of ionizing radiation relevant to radiodiagnostic procedures, very few studies have examined radiation schemes similar to those frequently utilized in CT exams. Instead of a single exposure, CT exams are often...
- Localization of a Female-Specific Marker on the Chromosomes of the Brown Seaweed Saccharina japonica Using Fluorescence In Situ Hybridization. Yu Liu; YanHui Bi; JunGang Gu; LiHua Li; ZhiGang Zhou // PLoS ONE;Nov2012, Vol. 7 Issue 11, Special section p1
Background: There is a heteromorphic alternative life in the brown seaweed, Saccharina japonica (Aresch.) C. E. Lane, C. Mayes et G. W. Saunders ( = Laminaria japonica Aresch.), with macroscopic monoecious sporophytes and microscopic diecious gametophytes. Female gametophytes are genetically...
- Differential Expression of Oxidative Stress and Extracellular Matrix Remodeling Genes in Low- or High-Dose-Rate Photon-Irradiated Skin. Mao, Xiao Wen; Mekonnen, Tsehay; Kennedy, Ann R.; Gridley, Daila S. // Radiation Research;Aug2011, Vol. 176 Issue 2, p187
Changes in the expression of genes implicated in oxidative stress and in extracellular matrix (ECM) remodeling and selected protein expression profiles in mouse skin were examined after exposure to low-dose-rate or high-dose-rate photon irradiation. ICR mice received whole-body Î³Î³ rays to...
- Preface. Cuttler, Jerry; Mitchel, Ron // Dose-Response;2006, Vol. 4 Issue 4, p255
A preface for the October 2006 issue of "Dose-Response" is presented.
- Letter to the Editor: Response to Epa Position on Cancer Risk from Low Level Radiation. Cohen, Bernard L. // Dose-Response;2010, Vol. 8 Issue 3, p384
No abstract available.