TITLE

Blood Donor Screening for Chagas Disease

AUTHOR(S)
Scully, Mary-Louise
PUB. DATE
April 2007
SOURCE
Travel Medicine Advisor;Apr2007, Vol. 17 Issue 4, p17
SOURCE TYPE
Periodical
DOC. TYPE
Article
ABSTRACT
A newly approved serologic assay for detecting Trypanosoma cruzi infection opens the door for universal screening of blood donations to prevent transfusion-transmitted Chagas disease.
ACCESSION #
24533203

 

Related Articles

  • Chronically Infected Patients with Trypanosoma cruzi Parasitemia: Further Support for Screening. Blackburn, Brian // Travel Medicine Advisor;Jan2009, Vol. 19 Issue 1, p1 

    Chagas disease (American trypanosomiasis) is caused by infection with the protozoan parasite Trypanosoma cruzi, and is spread primarily by triatomine insect vectors ("kissing bugs"). Although vector-borne transmission is primarily confined to rural Latin America, other routes of transmission...

  • Chagas Disease and the London Declaration on Neglected Tropical Diseases. Tarleton, Rick L.; Gürtler, Ricardo E.; Urbina, Julio A.; Ramsey, Janine; Viotti, Rodolfo // PLoS Neglected Tropical Diseases;Oct2014, Vol. 8 Issue 10, p1 

    The article discusses the nature of Chagas disease or American trypanosomiasis, a chronic parasitosis caused by the kinetoplastid parasite Trypanosoma cruzi. It notes the use of pyrethroid insecticides and application of blood donation screening designed to prevent and control the disease's...

  • Trypanosoma cruzi in Persons without Serologic Evidence of Disease, Argentina. Salomone, Oscar A.; Basquiera, Ana L.; Sembaj, Adela; Aguerri, Ana M.; Reyes, María E.; Omelianuk, Mirtha; Fernández, Ruth A.; Enders, Julio; Palma, Atilio; Barral, José Moreno; Madoery, Roberto J. // Emerging Infectious Diseases;Dec2003, Vol. 9 Issue 12, p1558 

    Current diagnosis of chronic Chagas disease relies on serologic detection of specific immunogiobulin G against Trypanosoma cruzi. However, the presence of parasites detected by polymerase chain reaction (PCR) in patients without positive conventional serologic testing has been observed. We...

  • Globalization of Chagas Disease: A Growing Concern in Nonendemic Countries. Klein, Nicole; Hurwitz, Ivy; Durvasula, Ravi // Epidemiology Research International;2012, p1 

    Chagas disease, caused by the parasite Trypanosoma cruzi, is a major cause of morbidity and mortality in Central and South America. Initial infection and ensuing chronic infection often go undetected in the human host. High seroprevalence of T. cruzi infection is well documented in endemic...

  • Enfermedad de Chagas y la seguridad transfusional en México. Malagón-Martínez, Araceli // Revista Medica del IMSS;mar/abr2010, Vol. 48 Issue 2, p117 

    The World Health Organization considers to the American trypanosomiasis a disease with priority attention that cause 45 000 deaths annually. We are celebrating a century of the disease description and the identification of etiologic agent and the transmitter. The universal screen strategy had...

  • Trypanosoma cruzi: evaluation of (−)-cubebin derivatives activity in the messenger RNAs processing. Silva, Márcio; Cicarelli, Regina; Pauletti, Patrícia; Luz, Priscilla; Rezende, Karen; Januário, Ana; Silva, Rosangela; Pereira, Ana; Bastos, Jairo; Albuquerque, Sérgio; Magalhães, Lizandra; Cunha, Wilson // Parasitology Research;Aug2011, Vol. 109 Issue 2, p445 

    No fully effective treatment has been developed since the discovery of Chagas' disease. Since drug-resistant Trypanosoma cruzi strains are occurring and the current therapy is effective in the acute phase but with various adverse side effects, more studies are needed to characterize the...

  • Human and Sylvatic Trypanosoma cruzi Infection in California. Navin, Thomas R.; Roberto, Ronald R.; Juranek, Dennis D.; Limpakarnjanarat, Khanchit; Mortenson, Earl W.; Clover, James R.; Yescott, Richard E.; Taclindo, Crispin; Steurer, Frank; Allain, Dorothy // American Journal of Public Health;Apr1985, Vol. 75 Issue 4, p366 

    In August 1982, a 56-year-old woman from Lake Don Pedro, California, developed acute Chagas' disease (American trypanosomiasis). She had not traveled to areas outside the United States with endemic Chagas' disease, she had never received blood transfusions, and she did not use intravenous drugs....

  • Usefulness of real time PCR to quantify parasite load in serum samples from chronic Chagas disease patients. Melo, Myllena F.; Moreira, Otacilio C.; Tenório, Priscila; Lorena, Virginia; Lorena-Rezende, Izaura; Júnior, Wilson Oliveira; Gomes, Yara; Britto, Constança // Parasites & Vectors;2015, Vol. 8 Issue 1, p1 

    Background: Inconclusive results of serological diagnosis in Chagas disease have an important impact on blood banks worldwide, reflecting in the high number of discarded bags or in an increased transmission by blood transfusion. Molecular techniques such as qPCR have been used for diagnosis and...

  • Sensitive and Specific Detection of Trypanosoma cruzi DNA in Clinical Specimens Using a Multi-Target Real-Time PCR Approach. Qvarnstrom, Yvonne; Schijman, Alejandro G.; Veron, Vincent; Aznar, Christine; Steurer, Francis; Da Silva, Alexandre J. // PLoS Neglected Tropical Diseases;Jul2012, Vol. 6 Issue 7, p1 

    Background: The laboratory diagnosis of Chagas disease is challenging because the usefulness of different diagnostic tests will depend on the stage of the disease. Serology is the preferred method for patients in the chronic phase, whereas PCR can be successfully used to diagnose acute and...

Share

Read the Article

Courtesy of VIRGINIA BEACH PUBLIC LIBRARY AND SYSTEM

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics