Schneikert, Jean; Behrens, Jürgen
March 2007
Gut;Mar2007, Vol. 56 Issue 3, p417
Academic Journal
The article explores the canonical Wnt signal transduction pathway in colorectal cancer. The canonical Wnt signaling cascades controls cell behavior by activating the transcriptional properties of Deoxyribonucleic Acid-binding proteins if the T cell factor/lymphoid enhancer factor-1 family. Several drugs, such as non-steroidal anti-inflammatory drugs, were established known to be effective in the treatment of colorectal cancer which turned out later to target the Wnt protein pathway.


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