Mechanisms of epithelial dysfunction in giardiasis

Buret, Andre G.
March 2007
Gut;Mar2007, Vol. 56 Issue 3, p316
Academic Journal
The article explores the pathological mechanisms in epithelial dysfunction by Giardia infection. The author argues that infection with intestinal parasite Giardia lamblia may cause acute or chronic diarrhea, dehydration, abdominal discomfort and weight loss. The parasite could cause disease without penetrating the epithelium, invading surrounding tissues or entering blood stream. However, epithelial abnormalities responsible for intestinal malabsorption and diarrhea seem to share similarities.


Related Articles

  • Giardia lamblia:. Huber, Jeffrey T.; Gillaspy, Mary L. // Encyclopedic Dictionary of AIDS-Related Terminology;2000, p99 

    A definition of the term "giardia lamblia" is presented. It refers to a species of giardia in humans. The species may cause giardiasis. The causative agent can be transmitted by ingestion of fecally-contaminated matter. The species can be contacted in all parts of the world. The term may also...

  • The Prevalence of Giardia Intestinalis in Dyspeptic and Diabetic Patients. Hakim, Gözde Derviş; Kızıltas, Şatak; Çiftçi, Hilmi; Göktaş, Şafak; Tuncer, İlyas // ISRN Gastroenterology;2011, Special section p1 

    Background and Aims. We aimed to investigate the prevalence of Giardiasis in patients with dyspepsia and patients with diabetes mellitus. Methods. 400 patients and 100 healthy persons were included in this clinical prospective study. The number of patients in each group was equal, 200 dyspeptic...

  • Small Intestine Studies in Giardiasis. Cantor, David; Biempica, Luis; Toccalino, Horacio; O'Donnell, Juan Carlos // American Journal of Gastroenterology;Feb1967, Vol. 47 Issue 2, p134 

    Presents information on a study regarding giardia lamblia found in small intestines of children. Elements that were compared in order to estimate morphologic alterations; Comparative analysis between giardiasis and malabsorption syndrome; Criteria for the selection of patients to be included in...

  • The course of giardiasis in Mongolian gerbils and SCID mice infected with new strains of Giardia lamblia. Sotiriadou, I.; Karanis, P. // Water Science & Technology: Water Supply;2004, Vol. 4 Issue 2, p63 

    The infectivity of Giardia isolates in Mongolian gerbils and in SCID mice inoculated with a newly established G. intestinalis strains of human origin (ISO/90/1, ISO/90/2) and a reference strain ATCC 30888 has been investigated. Inoculation of Mongolian gerbils with trophozoites resulted in an...

  • NAUSEA AND VOMITING, WITHOUT ABDOMINAL PAIN, DUE TO GIARDIASIS. Weingarten, Michael; Serwer, Jesse J. // American Journal of Gastroenterology;Feb1956, Vol. 25 Issue 2, p131 

    Focuses on the study about Giardiasis. Symptoms of gardiasis; Infestation of Giardia lamblia parasite as primary cause of the disease; Therapy applicable to Giardiasis.

  • © IS0ENZYME STUDIES OF GIARDIA LAMBLIA ISOLATED FROM SYMPTOMATIC CASES. Baveja, Usha K.; Jyoti, A. S.; Kaur, Manjit; Agarwal, D. S.; Anand, B. S.; Nanda, R. // Australian Journal of Experimental Biology & Medical Science;Apr1986, Vol. 64 Issue 2, p119 

    Strains of Giardia lamblia were isolated from symptomatic cases of giardiasis and axenized in the laboratory. Electrophoretic mobility patterns of four enzymes, viz., EC glucose phosphate isomerase (GPI); EC 1.1.1,4.0.1-malate; NADP+ Oxidoreductase (Oxaloacetate decarboxylating)...

  • Genotypes of Giardia intestinalis clinical isolates of gastrointestinal symptomatic and asymptomatic Saudi children. Al-Mohammed, Hamdan I. // Parasitology Research;Jun2011, Vol. 108 Issue 6, p1375 

    Giardiasis is the most worldwide parasitic disease with the major clinical impact on infant and children. Two genotypes were reported commonly among humans (assemblage A and B). In this study, genotypes of Giardia intestinalis clinical isolates obtaining from 24 gastrointestinal symptomatic...

  • giardiasis.  // Taber's Cyclopedic Medical Dictionary (2009);2009, Issue 21, p948 

    A definition of the term "giardiasis" is presented. It refers to the infection of the small intestine with the flagellate protozoan Giardia (G.) lamblia, also known as G. duodenalis and G. intestinalis. It happens when cysts are eaten or drank and parasitize the small bowel. During patient care,...

  • INACTIVATION OF GIARDIA LAMBLIA CYSTS BY COBALT-60 IRRADIATION. Sundermann, Christine A.; Estridge, Barbara H. // Journal of Parasitology;Apr2010, Vol. 96 Issue 2, p425 

    Cysts of Giardia lamblia can be a contaminant of water and food that can infect humans and cause the zoonotic disease giardiasis. Irradiation by a cobalt-60 source was investigated for its ability to inactivate cysts such that they would not be infective to gerbils. Cysts that received doses of...


Read the Article


Sign out of this library

Other Topics