Therapeutic potential of fractalkine: a novel approach to metastatic colon cancer

Brueckmann, M.; Borggrefe, M.
March 2007
Gut;Mar2007, Vol. 56 Issue 3, p314
Academic Journal
The article explores the therapeutic effect of fractalkine in metastatic colon cancer. Researchers argue that several experimental approaches have shown that variety of chemokines have anti-tumor activity either by chemoattracting natural killer cells, monocytes and macrophages or by accumulating dendritic cells. Evidence has shown that fractalkine, which is a unique membrane of CX3C chemokine subfamily, is involved in pathogenesis of different types of cancer.


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