TITLE

Therapeutic potential of fractalkine: a novel approach to metastatic colon cancer

AUTHOR(S)
Brueckmann, M.; Borggrefe, M.
PUB. DATE
March 2007
SOURCE
Gut;Mar2007, Vol. 56 Issue 3, p314
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
The article explores the therapeutic effect of fractalkine in metastatic colon cancer. Researchers argue that several experimental approaches have shown that variety of chemokines have anti-tumor activity either by chemoattracting natural killer cells, monocytes and macrophages or by accumulating dendritic cells. Evidence has shown that fractalkine, which is a unique membrane of CX3C chemokine subfamily, is involved in pathogenesis of different types of cancer.
ACCESSION #
24528552

 

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