Renal ischemia–reperfusion injury: Renal dendritic cells loudly sound the alarm

Nelson, P. J.
April 2007
Kidney International;Apr2007, Vol. 71 Issue 7, p604
Academic Journal
Renal ischemia–reperfusion injury is a major cause of acute renal failure and kidney allograft dysfunction. Dong and colleagues now identify the surveying renal dendritic cell network as the predominant source of tumor necrosis factor-α during the early stages of renal ischemia–reperfusion injury, raising the possibility for direct targeting of renal dendritic cells to help ameliorate this common form of renal injury and its sequelae.Kidney International (2007) 71, 604–605. doi:10.1038/sj.ki.5002121


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