Living donor kidney transplantation in a global environment

Delmonico, F. L.; Dew, M. A.
April 2007
Kidney International;Apr2007, Vol. 71 Issue 7, p608
Academic Journal
Live donor kidney transplantation has become a widely sought treatment by patients with end-stage renal failure. As the outcome for the genetically and emotionally related live donor transplants is the same, this review considers live kidney transplantation from the broad scope of current international practice. Unrelated live donor transplantation can now be performed for incompatible donor recipient pairs via a simultaneous paired kidney donation. However, acceptance of the scientific data that an unrelated live donor transplant can now be performed successfully should not be misconstrued as an acceptance that an unrelated kidney may be purchased via a vendor sale. At a recent World Health Organization (WHO) conference of Middle East transplant professionals a statement of unequivocal opposition to commercialism was drafted. In the United States, the Institute of Medicine has recently published a significant report that affirms the legal prohibition of organ sales. These documents are in accord with the guiding principles of the WHO and the membership policy of The Transplantation Society. The person who gives consent to be a donor should be competent, willing to donate, free of coercion, medically and psychosocially suitable, and fully informed of the risks and benefits as a donor. With these principles established, the Amsterdam Forum has set forth a comprehensive list of medical criteria that is now used internationally in the evaluation of potential kidney donors. Guidelines of a psychosocial evaluation are also presented in this report for individuals who come forward through internet solicitation and other public appeals. It is now evident that the annual number of available deceased donors will not resolve the ongoing shortage of organs. Nevertheless, live donor kidney transplantation may not be the realistic final solution to an international public health epidemic of renal failure that is the result of an aging population of patients that have had inadequate preventive medical care.Kidney International (2007) 71, 608–614. doi:10.1038/sj.ki.5002125; published online 7 February 2007


Related Articles

  • Dilemma over live-donor transplantation. Garwood, Paul // Bulletin of the World Health Organization;Jan2007, Vol. 85 Issue 1, p5 

    The article discusses issues related to kidney transplantation with special reference to Pakistan. Kidney donation is a widely recognized procedure in spite of some risks associated with it for living donors. The World Health Organization (WHO) stresses on increasing the supply of kidneys from...

  • Philippine slums a hotbed for the kidney black market.  // Filipino Post;9/9/2010, p13 

    The article reports on the black market for kidney or human organ trafficking in the Philippines. It cites data from the World Health Organization (WHO) claiming that the Philippines is one of the global hotspots for organ trafficking, along with China, Pakistan, Egypt, and Colombia. However, it...

  • Globally consistent coding systems for medical products of human origin. Warwick, Ruth M.; Chapman, Jeremy; Pruett, Timothy L.; Wang, Haibo // Bulletin of the World Health Organization;May2013, Vol. 91 Issue 5, p314 

    The authors reflect on globally consistent coding systems for medical products of human origin. They suggest that medical products of human origin, including blood, organs and bone marrow, provide important and often irreplaceable therapies. They argue that a globally consistent coding system...

  • Russia tightens up on transplants. Conradi, Peter // BMJ: British Medical Journal (International Edition);11/14/92, Vol. 305 Issue 6863, p1178 

    Focuses on the stand of the Russian government on the trade of organs for transplantation. Amendment of a law on conditions, procedures and penalties for transplant surgery; Provision of the law; Recommendations by the World Health Organization on the issue.

  • Current concerns in transplantation. Noël, Luc // Bulletin of the World Health Organization;Dec2007, Vol. 85 Issue 12, p905 

    The article discusses two reports published within the issue, one on ethical facets of cell and tissue transplantation and another one on the condition of the international organ trade as accounted by the World Health Organization.

  • International practices of organ donation. Rudge, C.; Matesanz, R.; Delmonico, F. L.; Chapman, J. // BJA: The British Journal of Anaesthesia;Jan2012 Supplement 1, Vol. 108, pi48 

    Organ donation and transplant rates vary widely across the globe, but there remains an almost universal shortage of deceased donors. The unmet need for transplants has resulted in many systematic approaches to increase donor rates, but there have also been practices that have crossed the...

  • Donor/Recipient Gender Have No Impact on Graft Function.  // Kidney;May/Jun98, Vol. 7 Issue 3, p127 

    Discusses the abstract of the research paper 'Influence of donor and recipient ages and sex on graft function after pediatric renal transplantation,' by U.B. Berg, A.-B. Bohlin et al and published in a 1997 issue of the journal 'Transplantation.'

  • Kidney Transplantation from Donors without a Heartbeat. Weber, Markus; Dindo, Daniel; Demartines, Nicholas; Ambühl, Patrice M.; Clavien, Pierre-Alain // New England Journal of Medicine;7/25/2002, Vol. 347 Issue 4, p248 

    Background: The dramatic shortage of kidney donors has triggered interest in other sources of organs, such as donors without a heartbeat. Accumulating evidence suggests that the short-term survival of cadaveric kidneys from such donors is similar to that of cadaveric kidneys from donors with a...

  • Donors without a Heartbeat. Cecka, J. Michael // New England Journal of Medicine;7/25/2002, Vol. 347 Issue 4, p281 

    Editorial. Focuses on the shortage of suitable kidneys available for transplantation in the United States. Reference to an article by Weber et al in this issue which raises the possibility that kidneys from donors whose hearts have stopped beating could expand the number of cadaveric kidneys...


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics