Pneumatic Dilatation or Laparoscopic Cardiomyotomy in the Management of Newly Diagnosed Idiopathic Achalasia

Kostic, S.; Kjellin, A.; Ruth, M.; Lönroth, H.; Johnsson, E.; Andersson, M.; Lundell, L.
March 2007
World Journal of Surgery;Mar2007, Vol. 31 Issue 3, p470
Academic Journal
The most effective therapeutic strategy in newly diagnosed achalasia is yet to be established. Therefore we designed a study in which pneumatic dilatation was compared to laparoscopic cardiomyotomy to which was added a partial posterior fundoplication. A series of 51 patients (24 males, mean age 44 years) were randomly allocated to the therapeutic modalities (dilatation = 26, surgery = 25). All patients were followed for at least 12 months, and during that period the pneumatic dilatations strategy had significantly more treatment failures ( P = 0.04). Only minor differences emerged between the study groups when symptoms, dysphagia scorings, and quality-of-life assessments were evaluated 12 months after initiation of therapy. Laparoscopic myotomy was found to be superior to an endoscopic balloon dilatation strategy in the treatment of achalasia when studied during the first 12 months after treatment.


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