TITLE

Determination of five nitrobenzoic acids in groundwater by solid-phase extraction and liquid chromatography—mass spectrometry

AUTHOR(S)
Wai-Tang Ma; Wan Chan; Steinbach, Klaus; Zongwei Cai
PUB. DATE
March 2007
SOURCE
Analytical & Bioanalytical Chemistry;Mar2007, Vol. 387 Issue 6, p2219
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
A method involving solid-phase extraction (SPE) and reversed-phase liquid chromatography–mass spectrometry (LC–MS) has been developed for determination, in groundwater, of nitrobenzoic acids associated with 2,4,6-trinitrotoluene production. Pre-concentration on a co-polymer-based SPE cartridge enabled quantitative extraction of the analytes from water. Investigation of negative ion electrospray and atmospheric-pressure chemical ionization mass spectrometry indicated the sensitivity of APCI was more than twice that of ESI. An 15N-labeled internal standard was used to achieve more accurate quantitation and mass assignment. Recovery was better than 80% when 10 mL water was extracted with the SPE cartridge. Combination of SPE with LC–MS analysis resulted in method detection limits of less than 5 μg L−1. The method has been used for analysis of groundwater samples collected from a site of a former ammunition plant. Contamination with nitrobenzoic acids was determined at μg L−1 levels.
ACCESSION #
24207452

 

Related Articles

Share

Read the Article

Courtesy of THE LIBRARY OF VIRGINIA

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics