TITLE

Systematic Method Developments for Analysis of Highly Water-Soluble Compounds by HPLC

AUTHOR(S)
Wang, Jerry
PUB. DATE
February 2007
SOURCE
LC-GC North America;Feb2007 Supplement, Vol. 25, p43
SOURCE TYPE
Trade Publication
DOC. TYPE
Article
ABSTRACT
The article presents an application note about the systematic method developments for analysis of highly water-soluble compounds by high performance liquid chromatography. According to the author, it a known fact that highly water-soluble compounds have often found difficulties in HPLC analysis such as lack of retention and bad peak shape or inconsistency. In application note, he will demonstrate such a method development scheme.
ACCESSION #
24104042

 

Related Articles

  • An Optical Sensor for the Determination of Ascorbic Acid. Gavrilenko, N. A.; Mokrousov, G. M.; Dzhiganskaya, O. V. // Journal of Analytical Chemistry;Sep2004, Vol. 59 Issue 9, p871 

    It is shown that an optically transparent polymethacrylate matrix modified with 2,2′-dipyridyl and iron(III) can be used as a sensor for ascorbic acid. A procedure for the solid-phase spectrophotometric and visual determination of ascorbic acid in model solutions and juices using this...

  • But I Can't Change the Method. Dolan, John W. // LC-GC North America;Jun2004, Vol. 22 Issue 6, p524 

    Focuses on a validated chromatographic method. Mobile phase; Flaw of the method; Design of the validated process for the method.

  • A metallofullerene that encapsulates 225Ac. Akiyama, K.; Haba, H.; Tsukada, K.; Asai, M.; Toyoshima, A.; Sueki, K.; Nagame, Y.; Katada, M. // Journal of Radioanalytical & Nuclear Chemistry;May2009, Vol. 280 Issue 2, p329 

    The properties of a metallofullerene that encapsulates 225Ac were studied by radio-chromatographic methods. The results of chromatography on a Buckyclutcher column suggest that there are some metallofullerene isomers of AcC82. The identical HPLC retention time of the major AcC82 peak with that...

  • Excellent Peak Shape and Productivity Gains from Eclipse Plus C8 Columns. Henderson Jr., John W. // LC-GC North America;Jun2007 Application Notebook Suppl, Vol. 25, p68 

    The article offers information about the ZORBAX Eclipse Plus C8 columns. The new technology in high performance liquid chromatography (HPLC) columns offer excellent peak shape for sensitivity and resolution and efficiency for acids, neutrals and bases. Eclipse Plus has unique silica treatment,...

  • New Horizons in Reversed-Phase Chromatography Selectivity. Snyder, Lloyd R.; Carr, Peter W.; DoIan, John W.; Majors, Ronald E. // LC-GC Europe;Jun2010, Vol. 23 Issue 6, p314 

    For decades, reversed-phase (RP) chromatography has dominated HPLC applications. Almost as soon as bonded reversed phases became available in the early 1970s, this mode surged ahead as the most popular. Through the years, the technique has become more efficient, columns more stable, and new...

  • Validation of a liquid Chromatography-Tandem Mass Spectrometry Method for Quantification of Glycopyrrolate in Horse Plasma. Rumpler, M. J.; Sams, R. A.; Colahan, P. // Journal of Analytical Toxicology;Nov/Dec2011, Vol. 35 Issue 9, p656 

    The article describes a sensitive and selective method for the direct quantification of glycopyrrolate (GLY) in horse plasma. The development of a method to detect and quantify glycopyrrolate in horse plasma has been validated through a specific ultra-high performance liquid chromatography with...

  • A Speciality Column for Surfactant Analysis. Xiaodong Liu; Heckenberg, Andrea; Pohl, Chris // LC-GC Europe;Dec2005 Supplement, Vol. 18, p24 

    The article describes the separation of cationic, nonionic and anionic surfactants using the Acclaim Surfactant specialty column. Separations were performed on a modular Summit High Performance Liquid Chromatography System equipped with a P680 gradient pump, ASI-100 Autosampler, TCC-100 column...

  • Determination of Anthocyanins by High-Performance Liquid Chromatography: Regularities of Retention. Deineka, V. I.; Grigor'ev, A. M. // Journal of Analytical Chemistry;Mar2004, Vol. 59 Issue 3, p270 

    The chromatographic behavior of anthocyanidin derivatives was studied by reversed-phase HPLC. Two types of increment functions in the retention of anthocyanidin glycosides were found. In the first type, an increment corresponding to the replacement of one glycoside with another in a series of...

  • HPLC Systems and Modules Introduced at Pittcon 2013: A Brief Review. Dong, Michael W. // LC-GC Asia Pacific;Jun2013, Vol. 16 Issue 2, p27 

    The article discusses the highlights of the Pittsburgh Conference on Analytical Chemistry and Applied Spectroscopy (Pittcon). It provides an overview and megatrends in modern high performance liquid chromatography (HPLC). Examples of new systems or system extension offerings are offered. Modules...

Share

Read the Article

Courtesy of THE LIBRARY OF VIRGINIA

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics