TITLE

Innovation in API Synthesis

AUTHOR(S)
Van Arnum, Patricia
PUB. DATE
February 2007
SOURCE
Pharmaceutical Technology;Feb2007, Vol. 31 Issue 2, p50
SOURCE TYPE
Trade Publication
DOC. TYPE
Article
ABSTRACT
The article reports that custom manufacturers are challenged by pharmaceutical industries to manufacture increasingly complex molecules with cost-effective routes. Degussa GmbH has taken a route to synthesize an enantiomerically pure aminolactam, a chiral building block for a new antithrombotic. BioCatalytics Inc. has developed a range of ketoreductases for the stereoselective reduction of ketones. Also, other companies are advancing biocatalysis for API synthesis.
ACCESSION #
23988685

Tags: ASYMMETRIC synthesis;  ORGANIC compounds -- Synthesis;  ENANTIOSELECTIVE catalysis;  ENANTIOMERS;  CHIRAL drugs;  DEGUSSA GmbH;  BIOCATALYTICS Inc.;  PHARMACEUTICAL industry

 

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