Innovation in API Synthesis

Van Arnum, Patricia
February 2007
Pharmaceutical Technology;Feb2007, Vol. 31 Issue 2, p50
Trade Publication
The article reports that custom manufacturers are challenged by pharmaceutical industries to manufacture increasingly complex molecules with cost-effective routes. Degussa GmbH has taken a route to synthesize an enantiomerically pure aminolactam, a chiral building block for a new antithrombotic. BioCatalytics Inc. has developed a range of ketoreductases for the stereoselective reduction of ketones. Also, other companies are advancing biocatalysis for API synthesis.


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