Deposition of fluoride on enamel surfaces released from varnishes is limited to vicinity of fluoridation site

Attin, T.; Lennon, A. M.; Yakin, M.; Becker, K.; Buchalla, W.; Attin, R.; Wiegand, A.
March 2007
Clinical Oral Investigations;Mar2007, Vol. 11 Issue 1, p83
Academic Journal
The aim of the in-situ study was to determine fluoride uptake in non-fluoridated, demineralized enamel after application of fluoride varnishes on enamel samples located at various distances from the non-fluoridated samples. All enamel samples used were demineralized with acidic hydroxyethylcellulose before the experiment. Intra-oral appliances were worn by ten volunteers in three series: (1, Mirafluorid, 0.15% F; 2, Duraphat, 2.3% F and 3, unfluoridated controls) of 6 days each. Each two enamel samples were prepared from 30 bovine incisors. One sample was used for the determination of baseline fluoride content (BFC); the other was treated according to the respective series and fixed in the intra-oral appliance for 6 days. Additionally, from 120 incisors, each four enamel samples were prepared (one for BFC). Three samples (a�c) were placed into each appliance at different sites: (a) directly neighboured to the fluoridated specimen (=next), (b) at 1-cm distance (=1 cm) and (c) in the opposite buccal aspect of the appliance (=opposite). At these sites, new unfluoridated samples were placed at days 1, 3 and 5, which were left in place for 1 day. The volunteers brushed their teeth and the samples with fluoridated toothpaste twice per day. Both the KOH-soluble and structurally bound fluoride were determined in all samples to determine fluoride uptake and were statistically analyzed. One day, after fluoridation with Duraphat, KOH-soluble fluoride uptake in specimen a (=next) was significantly higher compared to the corresponding samples of both the control and Mirafluorid series, which in turn were not significantly different from each other. At all other sites and time points, fluoride uptake in the enamel samples were not different from controls for both fluoride varnishes. Within the first day after application, intra-oral-fluoride release from the tested fluoride varnish Duraphat leads to KOH-soluble fluoride uptake only in enamel samples located in close vicinity to the fluoridation site.


Related Articles

  • Fluoridation; dental enamel: Changes in dental fluorosis following the cessation of water fluoridation. Watts, Trevor // British Dental Journal;1/13/2007, Vol. 202 Issue 1, p35 

    Parental rating of children's aesthetics did not show any difference related to fluoride.

  • 20 THINGS YOU DIDN'T KNOW ABOUT TEETH. Talkington, Megan // Discover;Sep2010, Vol. 31 Issue 7, p80 

    The article discusses several facts about teeth and dental care. Topics include the durability of tooth enamel, as well as its limitations and associated safety precautions, acid production by bacteria that leads to the development of cavities, and the introduction of the first fluoridated water...

  • Changes in the Fluoride-induced Modulation of Maturation Stage Ameloblasts of Rats. DENBESTEN, P. K.; CRENSHAW, M. A.; WILSON, M. H. // Journal of Dental Research;Dec1985, Vol. 64 Issue 12, p1365 

    The maturation stage of enamel development is characterized by a cyclic modulation of the ameloblasts between bands of smooth-ended cells and longer bands of ruffle-ended cells. There are cyclic patterns of calcein staining of and 45Ca uptake in the enamel associated with this cellular...

  • Does Caries in Primary Teeth Predict Enamel Defects in Permanent Teeth? A Longitudinal Study. Broadbent, J. M.; Thomson, W. M.; Williams, S. M. // Journal of Dental Research;Mar2005, Vol. 84 Issue 3, p260 

    The notion that caries in primary teeth causes developmental defects of enamel in permanent teeth has been recently revived. The research objective was to test this hypothesis through analysis of data from the Dunedin Multidisciplinary Health and Development Study, a longstanding prospective...

  • Systemic Fluoride. Borso, Heather // Access;Aug2009, Vol. 23 Issue 7, p23 

    The article focuses on the impact of fluoridated water on tooth decay, discusses the current guidelines on fluoride use and the fluoride content of accessed water sources. It is stated that fluoride not only prevents demineralization and promotes remineralization in the enamel, it also inhibits...

  • Comparison of the Effects of Two Topical Fluoride Regimens on Demineralized Enamel in vivo. CLARK, J. W.; CORPRON, R. E.; MORE, F. G.; EASTON, J. W.; MERRILL, D. F.; KOWALSKI, C. J. // Journal of Dental Research;Jun1988, Vol. 67 Issue 6, p954 

    The purpose of this investigation was to study the intra-oral remineralization of acid-softened enamel by a NaF dentifrice compared with that from a combination of topical F agents. Bovine enamel slabs were demineralized with 0.1 mol/L lactic acid at pH 4.0 for 14 hr and then mounted in are...

  • The Severity of Dental Fluorosis in Children Exposed to Water with a High Fluoride Content for Various Periods of Time. ISHII, T.; SUCKLING, G. // Journal of Dental Research;Jun1991, Vol. 70 Issue 6, p952 

    Inhabitants of the Ikeno district of Japan were accidentally exposed to drinking water containing 7.8 ppm fluoride (F) for 12 years, after which water with 0.2 ppm F was substituted. Dental examinations of local inhabitants revealed that only children aged seven years or less at the introduction...

  • DIAGNOdent: An Optical Method for Caries Detection. Lussi, A.; Hibst, R.; Paulus, R. // Journal of Dental Research;Jul2004 Supplement 1, pC80 

    The onset of caries is characterized by demineralization of dental hard tissues. Optimal fluoridation with respective oral hygiene habits and diet may stop the progression of a lesion and even allow for its remineralization. The aim of modern dentistry must be a preventive approach rather than...


    The article researches the effect of artificial water fluoridation on the solubility of tooth enamel. The research was designed to find out the acid solubility of deciduous enamel from children born before and at least six months after artificial fluoridation of a communal water supply. A...


Read the Article


Sign out of this library

Other Topics