The Effect of Stress-Reducing, Low-Dose Ethanol Infusion on Frequency of Bleeding Complications in Long-Term Alcoholic Patients Undergoing Major Surgery

Schoenfeld, Helge; Von Heymann, Christian; Lau, Alexandra; Krocker, Doerte; Neuner, Bruno; Schink, Tania; Schwenk, Wolfgang; Spies, Claudia D.
February 2007
American Surgeon;Feb2007, Vol. 73 Issue 2, p192
Academic Journal
Perioperative low-dose ethanol infusion is a feasible option for stress reduction and prophylaxis of alcoholism-associated complications. Because alcohol has inhibitory effects on hemostasis, our study focused on the effect of perioperative low-dose ethanol infusion on bleeding complications, defined as transfused blood units and reoperations, in alcoholic patients undergoing major surgery. We included 44 long-term alcoholic patients scheduled for tumor resection of the aerodigestive and gastrointestinal tract. Patients were randomly assigned to the ethanol or control group. Ethanol infusion (0.5 g ethanol/kg body weight/24 hours) started before surgery and was continued until the postoperative Day 3. Regarding all patients, there was no statistically significant difference in the amount of transfused blood between the ethanol and control groups. However, the effect of ethanol infusion on bleeding complications depended on the site of surgery. Ethanol infusion resulted in an increased number of transfused blood units in gastrointestinal patients and a decreased number of transfused units in patients undergoing tumor resection of the aerodigestive tract. In conclusion, perioperative ethanol infusion in long-term alcoholic patients with tumor resections of the aerodigestive tract is an option for stress reduction without increased risk for blood transfusion. In contrast, ethanol infusion in patients with tumor resections in the gastrointestinal tract could increase the risk for bleeding complications.


Related Articles

  • Stress relaxation behavior of nano-hydroxyapatite reinforced poly(vinyl alcohol) gel composites as biomaterial. Yusong Pan; Dangsheng Xiong // Journal of Materials Science;Oct2010, Vol. 45 Issue 20, p5495 

    Nano-hydroxyapatite reinforced poly(vinyl alcohol) (nano-HA/PVA) gel composites has been proposed as a promising biomaterial to replace diseased or damaged articular cartilage. In this paper, the stress relaxation mechanism of nano-HA/PVA gel composites was investigated. The various influence...

  • Don't let drinking become a refuge.  // USA Today Magazine;Feb95, Vol. 123 Issue 2597, p12 

    Focuses on the tendency of some people to drink alcohol for stress relaxation. Risks of relief drinking; Healthy outlets for stress and tension.

  • My good-night kiss was two double Jack Daniel's.  // Aging;1990, Issue 361, p2 

    Presents excerpts from personal accounts of recovering alcoholics. Among them is Athol Fugard's, a South African viewed as one of the world's most prominent playwrights.

  • Evaluating alcohol use in elders. Willenbring, M. // Aging;1990, Issue 361, p22 

    Discusses the role of the clinician in evaluating alcohol abuse in the elderly. The professional's attitude; Evaluation approaches; Screening techniques. INSET: Giving clients the `heat.'..

  • Older problem drinkers: A community treatment continuum. Dunlop, J.; Manghelli, D. // Aging;1990, Issue 361, p33 

    Describes the six components of a continuum, developed by a coalition from the Portland-Vancouver area, on alcoholism in the elderly. Prevention; Intervention; Detoxification. INSET: References..

  • TAP trains housing managers to help alcoholic tenants.  // Aging;1990, Issue 361, p41 

    Examines the Tenants Assistance Program for the Massachusetts Housing Finance Agency that has trained 1,500 property managers and staff on how to deal with tenants that abuse alcohol and drugs. What the training is designed to do; Objectives; The results of TAP's efforts. INSET: Treasure hunt..

  • A multimedia program on problem drinking in later life.  // Aging;1990, Issue 361, p43 

    Examines a multimedia community education workshop on alcohol problems in later life developed by a team of gerontologists and training specialists at Oregon State University. How it helps the person; `Winter Comforts,' a slide/sound media program; Cost of materials.

  • Utah's `Quality Aging,' broad-based prevention of problem drinking.  // Aging;1990, Issue 361, p44 

    Looks at the backdoor approach to alcohol abuse prevention used by the Quality Aging Program in Salt Lake City, Utah. This program sees alcoholism as an attempt to self medicate pain. Workshop topics; Gratifying aspects of the program; How seniors are learning new ways to cope.

  • Help for families and friends of alcoholics.  // Aging;1990, Issue 361, p49 

    Describes several groups and organizations that help family and friends of alcoholics. Al-Anon; Adult Children of Alcoholics (ACA); National Association for Children of Alcoholics (NACA). INSET: Advice for the family.;Books for families and friends of....


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics