Effects of atorvastatin and vitamin C on forearm hyperaemic blood flow, asymmentrical dimethylarginine levels and the inflammatory process in patients with type 2 diabetes mellitus

Tousoulis, Dimitris; Antoniades, Charalambos; Vasiliadou, Carmen; Kourtellaris, Pantelis; Koniari, Katerina; Marinou, Kyriakoula; Charakida, Marietta; Ntarladimas, Loannis; Siasos, Gerasimos; Stefanadis, Christodoulos
February 2007
Heart;Feb2007, Vol. 93 Issue 2, p244
Academic Journal
The article discusses a study that determines the effects of atorvastatin and vitamin C on forearm hyperaemic blood flow, asymmetrical dimethyl arginine (ADMA) levels and the inflammatory process in patients with type 2 diabetes mellitus (DM). The study involved 41 patients with type 2 DM and no proof of macroangiopathy. The findings imply that atorvastatin treatment can be beneficial in low-risk normocholesterolaemic patients with type 2 DM by improving endothelial function and lowering ADMA.


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