TITLE

Review: Low-dose aspirin causes a small increase in gastrointestinal bleeding

AUTHOR(S)
Chan, Francis K. L.
PUB. DATE
January 2007
SOURCE
ACP Journal Club;Jan/Feb2007, Vol. 146 Issue 1, p13
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
The article discusses a research study regarding the effect of low-dose aspirin on gastrointestinal (GI) bleeding and development of endoscopic ulcers. According to randomized placebo-controlled trials, low-dose aspirin results in an increase in GI bleeding. There is also an increase in the development of endoscopic ulcers. This is due to previous history of ulcers in patients, and the use of corticosteroids. The presence of helicobacter pylori enhances the risk for ulcer bleeding.
ACCESSION #
23847343

 

Related Articles

  • Peptic Ulcer Disease in Older People. Lockrey, Gregory; Lim, Lucy // Journal of Pharmacy Practice & Research;Mar2011, Vol. 41 Issue 1, p58 

    Peptic ulcer disease is a common disorder that affects millions of people worldwide. When complications occur, peptic ulcer disease can have a major impact on quality of life and on the utilisation of the health system. Understanding the causative roles of Helicobacterpylori and non-steroidal...

  • RISK FACTORS FOR GI BLEED. IANNI, ROSA; Dudley-Brown, Sharon // Clinical Advisor;Jul2011, Vol. 14 Issue 7, p71 

    The article provides an answer to a question concerning the risk factors of gastrointestinal bleed.

  • Antagonistic and synergistic interaction between Helicobacter pylori (Hp) and conventional nonsteroidal anti-inflammatory drugs (NSAID) and Coxibs during healing of preexisting gastric ulcers. Brzozowski, T.; Konturek, P.C.; Kwiecien, S.; Pajdo, R.; Sliwowski, Z.; Drozdowicz, D.; Bielanski, W.; Ptak, A.; Konturek, S.J.; Hahn, E.G. // Gut;Sep2002 Supplement 2, Vol. 51, pA59 

    Background: Hp and NSAID such as aspirin (ASA) are independent risk factors of gastric ulcerogenesis but interaction between them remains unclear. Aim: to compare the ulcer healing effects of gastric inoculation with viable Hp and its water extracts (WE) with those of vehicle in animals with or...

  • Aspirin inhibits the growth of Helicobacter pylori and enhances its susceptibility to antimicrobial agents. Wang, W.H.; Wong, W.M.; Dailidiene, D.; Berg, D.E.; Gu, Q.; Lai, K.C.; Lam, S.K.; Wong, B.C.Y. // Gut;Apr2003, Vol. 52 Issue 4, p490 

    Background and aim: The role of Helicobacter pylori and aspirin in peptic ulcer formation and recurrence remains an important clinical topic. The interaction between aspirin and H pylori in vitro is also not clear. We investigated the effect of aspirin on the growth of H pylori and on the...

  • Aspirin and Gastrointestinal Bleeding. Karpman, Harold L. // Internal Medicine Alert;5/15/2011, Vol. 33 Issue 9, p68 

    The author discusses a study which examined the risk of upper gastrointestinal bleeding (UGIB) in users of low-dose acetylsalicylic acid (ASA) and/or clopidogrel.

  • New England Journal of Medicine: Aspirin-clopidogrel no better than aspirin alone for patients with lacunar stroke.  // Biomedical Market Newsletter;8/28/2012, Vol. 21, p1 

    The article informs that people with lacunar strokes are at a higher risk of gastrointestinal bleeding if consume aspirin in combination with clopidogrel for stroke prevention.

  • Low dose aspirin safely reduced thrombosis in polycythaemia vera. Landolfi, R.; Marchioli, R. // BMJ: British Medical Journal (International Edition);4/10/2004, Vol. 328 Issue 7444, p0 

    Presents an abstract of a medical study to evaluate whether low dose aspirin is safe and effective for the prevention of thrombotic complications in patients with polycythemia vera. Report on an earlier study that was unsuccessful because of a high risk of gastrointestinal bleeding; Conclusion...

  • Aspirin ups risk of GI bleeding, but may reduce mortality.  // Reactions Weekly;12/12/2009, Issue 1282, p5 

    The article discusses research being done on the association between low-dose aspirin and peptic ulcer bleeding. It references the study "Continuation of Low-Dose Aspirin in Peptic Ulcer Bleeding: A Randomized Trial," by J. J. Y. Sung and colleagues, published in the December 1, 2009 issue of...

  • Possible role for aspirin in peptic ulcer therapy. Dragon, Natalie // GP: General Practitioner;4/7/2003, p4 

    This article focuses on the possible role for aspirin in peptic ulcer. Aspirin may be the key to treating drug-resistant Helicobacter pylori bacteria, and so prevent the onset of peptic ulcers. Researchers from Hong Kong found that aspirin inhibited the growth of all strains of H pylori they...

Share

Read the Article

Courtesy of VIRGINIA BEACH PUBLIC LIBRARY AND SYSTEM

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics