Review: Low-dose aspirin causes a small increase in gastrointestinal bleeding

Chan, Francis K. L.
January 2007
ACP Journal Club;Jan/Feb2007, Vol. 146 Issue 1, p13
Academic Journal
The article discusses a research study regarding the effect of low-dose aspirin on gastrointestinal (GI) bleeding and development of endoscopic ulcers. According to randomized placebo-controlled trials, low-dose aspirin results in an increase in GI bleeding. There is also an increase in the development of endoscopic ulcers. This is due to previous history of ulcers in patients, and the use of corticosteroids. The presence of helicobacter pylori enhances the risk for ulcer bleeding.


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