Atorvastatin reduced stroke and CV events after recent stroke or TIA in patients with no known coronary heart disease

Cheng, Eric
January 2007
ACP Journal Club;Jan/Feb2007, Vol. 146 Issue 1, p7
Academic Journal
The article cites a study regarding the effectiveness of atorvastatin in reducing stroke or transient ischemic attack (TIA) in patients not suffering from a coronary heart disease. The low-density lipoprotein cholesterol level was modified in patients with ischemic stroke. It was concluded that atorvastatin reduced stroke and coronary and cardiovascular events in patients with no known coronary heart disease and TIA. Atorvastatin proved more effective than placebo.


Related Articles

  • Secondary prevention for stroke and transient ischaemic attacks. Muir, Keith W // BMJ: British Medical Journal (International Edition);2/7/2004, Vol. 328 Issue 7435, p297 

    Reports on two trials have expanded options for secondary prevention after stroke and transient ischaemic attack. How in observational epidemiology studies no demonstrable floor exists for the relation between blood pressure and risk of stroke; Details of the perindopril protection against...

  • Dynamic analysis of optimality in myocardial energy metabolism under normal and ischemic conditions. Luo, Ruo-Yu; Liao, Sha; Tao, Guan-Yang; Li, Yuan-Yuan; Zeng, Shaoqun; Li, Yi-Xue; Luo, Qingming // Molecular Systems Biology;Vol. 2 Issue 1, pE1 

    To better understand the dynamic regulation of optimality in metabolic networks under perturbed conditions, we reconstruct the energetic-metabolic network in mammalian myocardia using dynamic flux balance analysis (DFBA). Additionally, we modified the optimal objective from the maximization of...

  • Prevention.  // Current Medical Literature: Stroke Review;2005, Vol. 9 Issue 4, p224 

    The article reflects on different citations and notes of clinicians about prevention of cardiovascular diseases. One of the clinicians' notes about the primary prevention of hypertension suggests that not all hypertensive drugs have similar efficacy. The other note suggests that patients need to...

  • Preventing further vascular events after a stroke or transient ischaemic attack: an updateon medical management. Sudlow, Cathie // Practical Neurology (BMJ Publishing Group);Jun2008, Vol. 8 Issue 3, p141 

    The article discusses guidelines for preventing further vascular events after a stroke, transient ischemic attack or intracerebral hemorrhage. Reducing blood pressure is important. Randomized controlled trials of antihypertensives confirmed that the more the blood pressure is lowered, the...

  • Experiences with carotid endarterectomy at Sree Chitra Tirunal Institute. Unnikrishnan, Madathipat; Siddappa, Shivananda; Anto, Rajesh; Babu, Vivek; Paul, Benny; Kapilamoorthy, Thirur Raman; Sivasankaran, Sivasubramanian; Sandhyamani, Samavedam; Sreedhar, Rupa; Radhakrishnan, Kuruppath // Annals of Indian Academy of Neurology;Jul2008, Vol. 11 Issue 3, p170 

    Background: Atherosclerotic carotid artery disease poses a grave threat to cerebral circulation, leading to a stroke with its devastating sequelae, if left untreated. Carotid endarterectomy has a proven track record with compelling evidence in stroke prevention. Objectives: a)To confirm that...

  • NMT's PFO/stroke device falls short of trial goal. PEDERSEN, AMANDA // Medical Device Daily;6/22/2010, Vol. 14 Issue 119, p1 

    The article reports that the Starflex device of NMT Medical did not meet its primary endpoint in the CLOSURE I trial for patent foramen ovale (PFO)/stroke and transient ischemic attack (TIA) trial in the U.S. The primary endpoint was to prove that the device is better than the current medical...

  • ACEP: Diagnose, treat TIAs more rapidly.  // ED Management;Oct2008, Vol. 20 Issue 10, p116 

    The article discusses the importance of quickly treating patients who have suffered a transient ischemic attack (TIA). The article notes that patients who have had a TIA are at risk of suffering a stroke. According to Andy Jagoda, emergency department medical director at Mount Sinai Hospital...

  • Stroke prevention in primary care.  // New Zealand Doctor;4/8/2009, p30 

    The article discusses several ways to prevent stroke in primary care. They include controlling risk factors, such as smoking, hypertension and identification and management of blood lipids. Another is modifying vascular risk factors after a transient ischemic attack. Among the secondary...

  • A Randomised Controlled Trial of Triple Antiplatelet Therapy (Aspirin, Clopidogrel and Dipyridamole) in the Secondary Prevention of Stroke: Safety, Tolerability and Feasibility. Sprigg, Nikola; Gray, Laura J.; England, Tim; Willmot, Mark R.; Zhao, Lian; Sare, Gillian M.; Bath, Philip M. W. // PLoS Clinical Trials;Aug2008, Vol. 5 Issue 8, p1 

    Background: Aspirin, dipyridamole and clopidogrel are effective in secondary vascular prevention. Combination therapy with three antiplatelet agents might maximise the benefit of antiplatelet treatment in the secondary prevention of ischaemic stroke. Methodology/Principal Findings:A randomised,...


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics