TITLE

The Expanding Role of LC-ICP-MS Speciation Analysis in the Life Sciences: Element-Selective Screening and Species-Independent Quantification

AUTHOR(S)
Zheng Yang; Neubauer, Kenneth
PUB. DATE
January 2007
SOURCE
LC-GC North America;Jan2007, Vol. 25 Issue 1, p56
SOURCE TYPE
Trade Publication
DOC. TYPE
Article
ABSTRACT
Emerging as a complementary analytical tool to liquid chromatography-mass spectrometry (LC-MS), LC-inductively coupled plasma-mass spectrometry (LC-ICP-MS) brings added value to the determination of inorganic element containing molecules of biological importance with its high selectivity, superior sensitivity, and nearly matrix-effect free determination. This article discusses the important roles LC-ICP-MS speciation analysis can play in meeting exploratory analytical challenges in the life sciences. Two promising capabilities of LC-ICP-MS that have the potential to broaden its applications in the life sciences but have not been investigated intensively and widely appreciated are emphasized: element-selective screening and species-independent quantification of organic compounds that contain one or more inorganic element, either naturally present in the compounds or intentionally introduced as an ICP-MS tag, such as P, S, Br, I, Si, Se, As, and metals.
ACCESSION #
23841763

 

Share

Read the Article

Courtesy of THE LIBRARY OF VIRGINIA

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics