Cerebral atrophy and skull thickening due to chronic phenytoin therapy

Chow, Kai Ming; Szeto, Cheuk Chun
January 2007
CMAJ: Canadian Medical Association Journal;1/30/2007, Vol. 176 Issue 3, p321
Academic Journal
journal article
The article evaluates the chronic phenytoin therapy in a patient with a history of refractory epilepsy and mental insufficiency with encephalitis. Clinical implications of skull thickening and cerebral atrophy are offered. The result of the CT scan after a head injury is presented. Effects of phenytoin on skull thickening are discussed.


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