Testosterone Use in Men With Sexual Dysfunction: A Systematic Review and Meta-analysis of Randomized Placebo-Controlled Trials
- Testosterone therapy in women: its role in the management of hypoactive sexual desire disorder. Abdallah, R. T.; Simon, J. A. // International Journal of Impotence Research;Sep2007, Vol. 19 Issue 5, p458
Disorders of sexual dysfunction occur in nearly half of women during their life, and hypoactive sexual desire disorder accounts for most of those complaints. Although the relationship between low endogenous testosterone levels and sexual desire disorders in women has not been empirically...
- What are the treatment options for SSRI-related sexual dysfunction? Sturpe, Deborah A.; Mertens, Marsha K.; Scoville, Caryn // Journal of Family Practice;Aug2002, Vol. 51 Issue 8, p681
This articles suggests various treatment options for SSRI-related sexual dysfunction. Augmentation therapy with multiple other agents may be effective. Three augmentation therapies have been tested in double-blind placebo-controlled trials. Buspirone augmentation led in an improvement in sexual...
- Viagra for Women? Phillips, Barbara A. // Internal Medicine Alert;8/29/2008, Vol. 30 Issue 16, p124
Women who had sexual dysfunction that was believed to be a side effect of antidepressants were more likely to report improved sexual function if they were assigned to the sildenafil, rather than to the placebo arm of a placebo-controlled trial.
- Is there a place for placebo controlled trials of antiepileptic drugs? Shorvon, S.D.; Espir, M.L.E.; Steiner, T.J.; Dellaportas, C.I.; Rose, F. Clifford // British Medical Journal (Clinical Research Edition);11/9/1985, Vol. 291 Issue 6505, p1328
Examines the possibility of a placebo controlled trials on antiepileptic drugs in Great Britain. Uncertainty on the role of anticonvulsant drugs on epileptics; Impact of epileptic seizures on the psychology and social behavior of epileptics; Natural history of epilepsy.
- Withholding Proven Treatment in Clinical Research. Huston, Patricia; Peterson, Robert // New England Journal of Medicine;9/20/2001, Vol. 345 Issue 12, p912
Editorial. Discusses the ethics of placebo-controlled clinical trials. Role of the Declaration of Helsinki; Need for scientific and ethical justification of the use of placebos.
- Is the Placebo Powerless? Hróbjartsson, Asbjørn; Gøtzsche, Peter C. // New England Journal of Medicine;05/24/2001, Vol. 344 Issue 21, p1594
Background: Placebo treatments have been reported to help patients with many diseases, but the quality of the evidence supporting this finding has not been rigorously evaluated. Methods: We conducted a systematic review of clinical trials in which patients were randomly assigned to either...
- An Evaluation of Arbaprostil at Multiple Doses for the Treatment of Acute Duodenal Ulcer: A Randomized Double Blind Placebo-Controlled International Trial. Euler, A. R.; Krawiec, J.; Odes, H.; Gilat, T.; Garcia, L.; Rachmilewitz, D.; Gabryelewicz, A.; Gibinski, K.; Bass, D.; Barbara, L.; Porro, G. Bianchi; Lazzaroni, M.; Kirchmayer, S.; Nago-Nago, A.; Popiela, T.; Kulig, J.; Roca, M.; Hagenmuller, F.; Bergemann, W.; Schryver, M. // American Journal of Gastroenterology;Feb1990, Vol. 85 Issue 2, p145
Six hundred and thirty patients were enrolled in a randomized double-blind placebo-controlled trial evaluating two arbaprostil dosages (25 Âµg and 50 Âµg) qid for 4 wk for the treatment of acute duodonal ulcers. The healing rates in the placebo, 25-Âµg, and 50-Âµg treatment groups were...
- Importance of Placebo Effect in Cough Clinical Trials. Eccles, Ron // Lung;Feb2010 Supplement 1, Vol. 188, p53
Cough is a unique symptom because, unlike sneeze and other symptoms, it can be under voluntary control and this complicates clinical trials on cough medicines. All over-the-counter cough medicines (OTC) are very effective treatments because of their placebo effect. The placebo effect is enhanced...
- Growth hormone reduced HIV-related visceral fat. // Hem/Onc Today;11/10/2008, Vol. 9 Issue 20, p40
The article discusses findings of a randomized, double-blind, placebo-controlled trial that was conducted by researchers from Massachusetts General Hospital in Boston, which examined the efficacy of low-dose growth hormone on body composition, glucose and cardiovascular factors as observed among...