TITLE

vCJD and the gut: implications for endoscopy

AUTHOR(S)
Head, M. W.; Ironside, J. W.
PUB. DATE
January 2007
SOURCE
Gut;Jan2007, Vol. 56 Issue 1, p9
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
The article focuses on the implications of Creutzfeldt-Jakob disease (CJD) for endoscopy. The cause of the disease was proposed to be oral exposure to the bovine encephalopathy agent as supported by subsequent studies made. The pathogenesis of prion diseases has been aided by the development of methods to detect and localize abnormal forms pf the prion protein.
ACCESSION #
23627613

 

Related Articles

  • Buying time.  // New Scientist;04/21/2001, Vol. 170 Issue 2287, p13 

    Reports on research effort at the University of California which attempts to slow onset and spread of prion diseases such as Creutzfeldt-Jakob disease (CJD) through use of alien prions. Effect of PrP proteins from a hamster on a mouse infected with abnormal PrP; Problems with delivery;...

  • A suspicious signature. Aguzzi, Adriano; Weissmann, Charles // Nature;10/24/1996, Vol. 383 Issue 6602, p666 

    Provides background and commentary of a study that describes a new approach for tracing the passage of individual prion strains within and between species. The suggestion that a variant of Creutzfeldt-Jakob disease (vCJD) resembles bovine spongiform encephalopathy (BSE) rather than acquired or...

  • Variably Protease-Sensitive Prionopathy, a Unique Prion Variant with Inefficient Transmission Properties. Diack, Abigail B.; Ritchie, Diane L.; Peden, Alexander H.; Brown, Deborah; Boyle, Aileen; Morabito, Laura; Maclennan, David; Burgoyne, Paul; Jansen, Casper; Knight, Richard S.; Piccardo, Pedro; Ironside, James W.; Manson, Jean C. // Emerging Infectious Diseases;Dec2014, Vol. 20 Issue 12, p1969 

    Variably protease-sensitive prionopathy (VPSPr) can occur in persons of all codon 129 genotypes in the human prion protein gene (PRNP) and is characterized by a unique biochemical profile when compared with other human prion diseases. We investigated transmission properties of VPSPr by...

  • Creutzfeldt-Jakob Disease: Recommendations for Disinfection and Sterilization. Weinstein, Robert A.; Rutala, William A.; Weber, David J. // Clinical Infectious Diseases;5/1/2001, Vol. 32 Issue 9, p1348 

    Presents recommendations for the disinfection and sterilization of medical devices contaminated by Creutzfeldt-Jakob disease (CJD). Etiology of prion diseases; Epidemiology of CJD; Details on a variant of CJD.

  • Psychotropic Medications and the Treatment of Human Prion Diseases. Appleby, Brian S. // CNS & Neurological Disorders - Drug Targets;2009, Vol. 8 Issue 5, p353 

    Prion diseases are rare, rapidly progressive, fatal neurodegenerative illnesses caused by an abnormal isoform of the native prion protein. Creutzfeldt-Jakob disease (CJD) is the most prevalent human prion disease with three possible etiologies: sporadic, genetic, and acquired. Although...

  • Molecular analysis of prion strain variation and the aetiology of `new variant' CJD. Collinge, John; Sidle, Katie C.L. // Nature;10/24/1996, Vol. 383 Issue 6602, p685 

    Presents a study of the physico-chemical properties of PrP(Sc) of strains of transmissible spongiform encephalopathies. The strain characteristics of a new variant of Creutzfeldt-Jakob disease (CJD); The suggestion that the prion protein may encode disease phenotype; The characteristics of...

  • New variant Creutzfeldt-Jakob disease: the epidemic that never was. Venters, George A // BMJ: British Medical Journal (International Edition);10/13/2001, Vol. 323 Issue 7317, p858 

    Examines the evidence for a causal link between new variant Creutzfeldt-Jakob disease and the bovine spongiform encephalopathy prion and argues in favour of the alternative hypotheses that the variant is not caused by the prion and is not new. Criteria to assess causality, including biological...

  • Variably protease-sensitive prionopathy in the UK: a retrospective review 1991–2008. Head, Mark W.; Yull, Helen M.; Ritchie, Diane L.; Langeveld, Jan P.; Fletcher, Nicholas A.; Knight, Richard S.; Ironside, James W. // Brain: A Journal of Neurology;Apr2013, Vol. 136 Issue 4, p1102 

    Variably protease-sensitive prionopathy is a newly described human prion disease of unknown aetiology lying out with the hitherto recognized phenotypic spectrum of Creutzfeldt–Jakob disease. Two cases that conform to the variably protease-sensitive prionopathy phenotype have been...

  • The Role of PrP in Health and Disease. Flechsig, F.; Weissmann, C. // Current Molecular Medicine;Jun2004, Vol. 4 Issue 4, p337 

    Transmissible spongiform encephalopathies (TSEs) such as scrapie in sheep, bovine spongiform encephalopathy (BSE) in cattle or Creutzfeldt-Jacob disease (CJD) and Gerstmann- Straussler-Scheinker syndrome (GSS) in humans, are caused by an infectious agent designated prion. The “protein...

Share

Read the Article

Courtesy of VIRGINIA BEACH PUBLIC LIBRARY AND SYSTEM

Sign out of this library

Other Topics