TITLE

Microbial interactions in Staphylococcus epidermidis biofilms

AUTHOR(S)
Mack, Dietrich; Davies, Angharad P.; Harris, Llinos G.; Rohde, Holger; Horstkotte, Matthias A.; Knobloch, Johannes K.-M.
PUB. DATE
January 2007
SOURCE
Analytical & Bioanalytical Chemistry;Jan2007, Vol. 387 Issue 2, p399
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Medical device-associated infections, most frequently caused by coagulase-negative staphylococci, especially Staphylococcus epidermidis, are of increasing importance in modern medicine. The formation of adherent, multilayered bacterial biofilms is the most important factor in the pathogenesis of these infections, which regularly fail to respond to appropriate antimicrobial therapy. Progress in elucidating the factors functional in elaboration of S. epidermidis biofilms and the regulation of their expression with a special emphasis on the role of quorum sensing are reviewed. Significant progress has been made in recent years, which provides the rationale for developing better preventive, therapeutic and diagnostic measures.
ACCESSION #
23616536

 

Related Articles

Share

Read the Article

Courtesy of THE LIBRARY OF VIRGINIA

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics