TITLE

DESPITE BENEFITS, GENE EXPRESSION FACES HURDLES

PUB. DATE
January 2007
SOURCE
Worldwide Biotech;Jan2007, Vol. 19 Issue 1, p4
SOURCE TYPE
Trade Publication
DOC. TYPE
Article
ABSTRACT
The article reports on the challenges facing gene expression. The benefits of gene sequence and gene expression analysis are enumerated, including the detection of defective genes and polymorphisms. According to Amarpreet Dhiman of Frost & Sullivan, gene expression develops new therapeutics and sub-classify patients based on the abnormal changes observed in their specific cells.
ACCESSION #
23549866

 

Related Articles

  • Epigenetic Cancer Therapy Makes Headway. Mack, George S. // JNCI: Journal of the National Cancer Institute;10/18/2006, Vol. 98 Issue 20, p1443 

    The article focuses on the investigation of the science of epigenetics by oncologists, to discover innovative methods for the treatment of cancer. Epigenetic therapy produces remissions. The therapy helps the patients live longer, healthier lives with less toxicity. The therapeutic concept works...

  • 824. Control of Splicing Efficiency by the Mouse Histone H2a Element in an MLV-Based Retroviral Vector. Jun-Tae Lee; Seung Shin Yu; Kim, V. Narry; Joong-Gon Kim; Youngtae Hong; Sujeong Kim; Karim Lee; Sun Mee Bae; Kyung Mi Koh; Hye Lim Cho; Sunyoung Kim // Molecular Therapy;Jun2006, Vol. 13, pS319 

    While using various human cDNA sequences in the context of the MLV-based retroviral vector, it was found that a retroviral vector containing some human cDNA sequences produces unusually low viral titer, as compared with the identical vector but harboring different sequences. One of those...

  • Rejuvenation of Gene Expression Pattern of Aged Human Skin by Broadband Light Treatment: A Pilot Study. Chang, Anne Lynn S; Bitter, Patrick H; Qu, Kun; Lin, Meihong; Rapicavoli, Nicole A; Chang, Howard Y // Journal of Investigative Dermatology;Jun2013, Vol. 133 Issue 6, p1691 

    A correction to the article "Rejuvenation of Gene Expression Pattern of Aged Human Skin by Broadband Light Treatment: A Pilot Study," by Anne Lynn S. Chang and colleagues that was published in the August 30, 2012 issue of the "Journal of Investigative Dermatology," is presented.

  • Gene expression: An importin-? stress response. Schuldt, Alison // Nature Reviews Molecular Cell Biology;Nov2011, Vol. 12 Issue 11, p693 

    The article discusses a research being done on the gene expression of importin-α stress response which references the study "Nuclear retention of importin-α coordinates cell fate through changes in gene expression," by Y. Yasuda and colleagues in the September 30, 2011 issue.

  • Tunable gene regulation. Dove, Alan // Nature Biotechnology;Nov98, Vol. 16 Issue 11, p994 

    Reports that researchers have developed a general approach for regulating gene expression at the level of translations. Overview of the technique; Features of the technique.

  • Correction: cDNA-AFLP analysis reveals differential gene expression in compatible interaction of wheat challenged with Puccinia striiformis f. sp. tritici.  // BMC Genomics;2013, Vol. 14 Issue 1, p1 

    A correction to the article "cDNA-AFLP analysis reveals differential gene expression in compatible interaction of wheat challenged with Puccinia striiformis f. sp. tritici.," that was published in a previous issue is presenetd.

  • Tissue Compartment Analysis for Biomarker Discovery by Gene Expression Profiling.  // PLoS ONE;2009, Vol. 4 Issue 11, p1 

    The article discusses a study which developed a tissue compartment analysis (TCA) method to assess the cell composition of tissue samples, and applied it to standardize data and to identify biomarkers. TCA method in the study was developed with human kidney samples, as an example of highly...

  • 747. Plasmid Electrotransfer of Eye Ciliary Muscle: Principle and Therapeutic Efficacy in an Acute Inflammatory Model. Bloquel, Carole; Bejjani, R.; Bigey, Pascal; Bedioui, Fethi; Doat, M.; BenEzra, David; Behar-Cohen, Francine; Scherman, Daniel // Molecular Therapy;Jun2006, Vol. 13, pS289 

    Due to its small size and particular isolating barriers, the eye is an ideal target for local therapy. The ocular delivery of recombinant proteins requires invasive and painful repeated injections. Alternatively, a transfected tissue might be used as a local producer of transgene-encoded...

  • Mistakes in validating the accuracy of a prediction classifier in high-dimensional but small-sample microarray data. Sunho Lee // Statistical Methods in Medical Research;Dec2008, Vol. 17 Issue 6, p635 

    A major interest in gene expression microarray studies is to develop an accurate classifier which can be adopted in clinical practice. The usage of large numbers of genes with small data samples may lead to overfitting in classification, and generate promising, but often nonreproducible results....

Share

Read the Article

Courtesy of THE LIBRARY OF VIRGINIA

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics