Deficient innate immunity and susceptibility of asthmatics to infection

Adams, A.
December 2006
Thorax;Dec2006, Vol. 61 Issue 12, p1053
Academic Journal
The article examines the mechanism in the pathogenesis of asthma exacerbations. The primary bronchial epithelial cells from asthmatic and normal subjects infected with the virus and viral RNA expression have been measured. It was found that viral replication was increased in cells from asthmatics than in normal subjects. Levels of messenger RNA encoding the type III interferon is inversely related to viral RNA levels.


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