Recent advances in capillary electrophoretic analysis of individual cells

Arcibal, Imee G.; Santillo, Michael F.; Ewing, Andrew G.
January 2007
Analytical & Bioanalytical Chemistry;Jan2007, Vol. 387 Issue 1, p51
Academic Journal
Because variability exists within populations of cells, single-cell analysis has become increasingly important for probing complex cellular environments. Capillary electrophoresis (CE) is an excellent technique for identifying and quantifying the contents of single cells owing to its small volume requirements and fast, efficient separations with highly sensitive detection. Recent progress in both whole-cell and subcellular sampling has allowed researchers to study cellular function in the areas of neuroscience, oncology, enzymology, immunology, and gene expression. [Figure not available: see fulltext.]


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