TITLE

Temperature gradient focusing for microchannel separations

AUTHOR(S)
Shackman, Jonathan Jonathan G. Shackman & Matthew S. Munson & Jonathan G.; Munson, Matthew S.; Ross, David
PUB. DATE
January 2007
SOURCE
Analytical & Bioanalytical Chemistry;Jan2007, Vol. 387 Issue 1, p155
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
The article describes the use of temperature gradient focusing (TGF) for microchannel separations. TGF is based upon balancing analytes' electrophoretic mobilities against a bulk flow containing hydrodynamic and electroosmotic flow components. It works by balancing the electrophoretic motion of analyte molecules against the bulk flow of solution through a separation channel. The electrophoretic velocity gradient is ensured by applying a temperature gradient along the length of the channel.
ACCESSION #
23460816

 

Related Articles

  • Dispersion due to wall interactions in microfluidic separation systems. Datta, Subhra; Ghosal, Sandip // Physics of Fluids;Jan2008, Vol. 20 Issue 1, p012103 

    The transport of a solute in a straight microchannel of axially variable cross-sectional shape in the presence of an inhomogeneous flow field and an adsorption-desorption process on the wall is studied, motivated by applications to capillary electrophoresis and open-channel capillary...

  • Thermocapillary manipulation of droplets using holographic beam shaping: Microfluidic pin ball. Cordero, Maria Luisa; Burnham, Daniel R.; Baroud, Charles N.; McGloin, David // Applied Physics Letters;7/21/2008, Vol. 93 Issue 3, p034107 

    We demonstrate that holographically generated optical patterns offer greater flexibility for the thermocapillary control of water droplets than Gaussian spots; droplets can be stopped in faster flows while using less optical intensity when the surface tension variations are created by line...

  • Capillary-based microfluidic analysis systems. Qun Fang; Meng Sun; Yan-Zhen Huang // Analytical & Bioanalytical Chemistry;Jan2009, Vol. 393 Issue 1, p63 

    An overview of the recent development of high-throughput capillary-based microfluidic analysis systems (CBMAS) is presented. The advantages and applications of these systems are discussed and illustrated by recent results obtained in the authors’ group and other groups. A possible outlook...

  • Capillary turbulence on the surface of normal and superfluid 4He. Abdurakhimov, L. V.; Brazhnikov, M. Yu.; Levchenko, A. A. // Low Temperature Physics;Feb2009, Vol. 35 Issue 2, p95 

    The capillary turbulence on the surface of liquid helium with excitation of surface waves by a harmonic force at low frequency ωp is investigated. It is shown for the first time that at the transition of helium out of the superfluid into the normal state the high-frequency edge ωb of the...

  • Capillary rise in nesting cylinders. Brady, Victor; Concus, Paul; Finn, Robert // Physics of Fluids;Jun2003, Vol. 15 Issue 6, p1545 

    We investigate computationally recent results concerning the question of whether liquid necessarily rises higher in a capillary tube of smaller section, when tubes are placed vertically in an infinite reservoir. The numerical results corroborate for a particular example a striking discontinuous...

  • Control of electro-osmostic flow by light. Oroszi, László; Dér, András; Kirei, Huba; Ormos, Pál; Rakovics, Vilmos // Applied Physics Letters;12/25/2006, Vol. 89 Issue 26, p263508 

    The author introduce a technique for the optical control of electro-osmosis. One wall of the microfluidic channel is formed by a photoconductive material. Illumination of the photoconductor results in a local drop of the electric field in the microchannel, reducing the electro-osmotic driving...

  • Collective effects of temperature gradients and gravity on droplet coalescence. Zhang, Xiaoguang; Wang, Hua; Davis, Robert H. // Physics of Fluids A;Jul93, Vol. 5 Issue 7, p1602 

    The interaction and coalescence of small spherical drops in dilute, homogeneous dispersions are considered theoretically under conditions, where drop motion results from gravity settling and thermocapillary migration acting simultaneously. A trajectory analysis is used to predict pairwise...

  • Special Solutions of some Generalized NLS Equations. Visinescu, Anca; Grecu, Dan; Fedele, Renato; De Nicola, Sergio // AIP Conference Proceedings;5/17/2009, Vol. 1131 Issue 1, p36 

    Using a Madelung fluid description a discussion is given for some generalized NLS equations. Solitary wave and periodic solutions are obtained for constant and stationary profile current velocity.

  • Capillary electrophoresis in contemporary analytical chemistry. Kaljurand, Mihkel // Proceedings of the Estonian Academy of Sciences, Chemistry;Mar2004, Vol. 53 Issue 1, p3 

    Examines the capillary electrophoresis in contemporary analytical chemistry. Phenomenon of migration of charged species; Influence of externally applied electric field; Differences in the mobility of the analytes.

Share

Read the Article

Courtesy of THE LIBRARY OF VIRGINIA

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics