Necrotizing Skin Ulceration in Antibiotic-Induced Agranulocytosis

Gössl, Mario; Eggebrecht, Holger
December 2006
Mayo Clinic Proceedings;Dec2006, Vol. 81 Issue 12, p1527
Academic Journal
The article cites a case of a thirty-one year old man who was diagnosed of acute agranulocytosis. The old man exhibited rapid-onset facial swelling with central necrosis and multiple purulent acne pustules upon admission to the West German Heart Center Essen in Germany. He was treated with floxacillin, minocycline, ampicillin or sulbactam, gentamicin and was injected with cortisone. After ten days of treatment, the clinical condition of the patient improved, with near normal serologic values.


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