Right ventricular reverse remodelling after sildenafil in pulmonary arterial hypertension

Van Wolferen, S. A.; Boonsfra, A.; Marcus, J. T.; Marques, K. M. J.; Bronzwaer, J. G. F.; Postmus, P. E.; Vonk-Noordegraaf, A.
December 2006
Heart;Dec2006, Vol. 92 Issue 12, p1860
Academic Journal
The article focuses on the addition of sildenafil reverses right ventricular (RV) modeling in patients with pulmonary arterial hypertension treated with bosentan. Side effects associated with the addition of the drug include headache, heartburn and epistaxis. RV mass has reduced significantly after the addition of sildenafil. This drug reverses RV dilatation and hypertrophy in patients already receiving treatment.


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