TITLE

Psychiatric Adverse Effects of Corticosteroids

AUTHOR(S)
Warrington, Thomas P.; Bostwick, J. Michael
PUB. DATE
October 2006
SOURCE
Mayo Clinic Proceedings;Oct2006, Vol. 81 Issue 10, p1361
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Psychiatric adverse effects during systemic corticosteroid therapy are common. Two large meta-analyses found that severe reactions occurred in nearly 6% of patients, and mild to moderate reactions occurred in about 28%. Although disturbances of mood, cognition, sleep, and behavior as well as frank delirium or even psychosis are possible, the most common adverse effects of short-term corticosteroid therapy are euphoria and hypomania. Conversely, long-term therapy tends to induce depressive symptoms. Dosage is directly related to the incidence of adverse effects but is not related to the timing, severity, or duration of these effects. Neither the presence nor the absence of previous reactions predicts adverse responses to subsequent courses of corticosteroids. Corticosteroid-induced symptoms frequently present early in a treatment cycle and typically resolve with dosage reduction or discontinuation of corticosteroids. In severe cases or situations in which the dose cannot be reduced, antipsychotics or mood stabilizers may be required. This review offers an approach to identifying and managing corticosteroid-induced psychiatric syndromes based on the type of symptoms and anticipated duration of corticosteroid treatment.
ACCESSION #
23272669

 

Related Articles

  • Familial multiple sclerosis with repetitive relapses of manic psychosis in two patients (mother and daughter). Modrego, Pedro J.; Ferrández, Jaime // Behavioural Neurology;2000, Vol. 12 Issue 4, p175 

    The clinical presentation of multiple sclerosis (MS) with psychiatric symptoms is uncommon but it is believed that MS patients are twice as likely to be afflicted with bipolar disorder as the general population. We report two cases (mother and daughter) of MS presenting with bipolar disorder in...

  • Periferik yüz felci geçirmiÅŸ olan bir hastada kısa süreli kortikosteroid kullanımı sonrasında ortaya çıkan karma mani atağı: Bir olgu sunumu. Balıbey, Hakan; Yaşar, Halit; Tekeli, Hakan // Journal of Mood Disorders;Mar2012, Vol. 2 Issue 1, p17 

    Corticosteroids are routinely used in the treatment of peripheral facial palsy. Affective symptoms have been reported as a possible side effect due to use of corticosteroids. After corticosteroid use psychiatric symptoms are often seen in the first weeks. More than half of them are seen in the...

  • A 15-year open study on a cohort of West-African out-patients with a chronic psychosis. de Jong, Joop T. V. M.; Komproe, I. H. // Social Psychiatry & Psychiatric Epidemiology;Nov2006, Vol. 41 Issue 11, p897 

    We wanted to find out if the additional costs of depot neuroleptic in comparison to oral medication was justified by a decrease in admission days. An open study on a cohort of chronic psychotic out-patients ( n = 45) consisting of a retrospective 10-year period on oral medication followed by a...

  • Perospirone.  // Reactions Weekly;12/9/2006, Issue 1131, p28 

    The article presents a case report of an elderly female patient who developed neuroleptic malignant syndrome during treatment with perospirone for corticosteroid-induced psychotic disorder, with reference to a study by M. Nakagawa, T. Matsumura et al. in the October 2006 issue of the...

  • Treatment Engagement of Psychotic Patients with a Mobile Mental Health Unit in Rural Areas in Greece: A Five-Year Study. Peritogiannis, Vaios; Tatsioni, Athina; Menti, Nefeli; Grammeniati, Aikaterini; Fotopoulou, Vassiliki; Mavreas, Venetsanos // Schizophrenia Research & Treatment;2013, p1 

    Objectives. Treatment of psychotic disorders is impended by high rates of disengagement from mental health services and poor adherence to antipsychotic medication. This study examined the engagement rates of psychotic patients with a community mental health service during a 5-year period....

  • Non-adherence to antipsychotic medication regimens: associations with resource use and costs. Knapp, Martin; King, Derek; Pugner, Klaus; Lapuerta, Pablo // British Journal of Psychiatry;Jun2004, Vol. 184, p509 

    Background Several factors are thought to influence resource use and costs in treating schizophrenia. Aims To assess the relative impact of non-adherence and other factors associated with resource use and costs incurred by people with schizophrenia. Method Secondary analyses were made of data...

  • Nithsdale Schizophrenia Surveys 17. Kelly, C.; McCreadie, R. G.; MacEwan, T.; Carey, S. // British Journal of Psychiatry;Jun98, Vol. 172, p513 

    Background In recent years there has been a shift to ‘community care’ and the introduction of several ‘typical’ antipsychotic drugs .We report the impact of these changes. Method In Nithsdale, Dumfries and Galloway, Scotland, the population of patients with...

  • Aripiprazole in the Treatment of Schizophrenia: A Consensus Report produced by Schizophrenia Experts in Italy. Cassano, Giovan B.; Fagiolini, Andrea; Lattanzi, Lorenzo; Monteleone, Palmiero; Niolu, Cinzia; Sacchetti, Emilio; Siracusano, Alberto; Vita, Antonio // Clinical Drug Investigation;2007, Vol. 27 Issue 1, p1 

    Schizophrenia is generally a chronic and disabling mental illness. Pharmacological therapy, which is used for relief of acute psychotic episodes and prevention of subsequent relapse, is essential for the effective management of schizophrenia. In order to alleviate the positive symptoms of...

  • MINDS AT RISK: CHOOSING THE RIGHT PATH FOR ADOLESCENT MENTAL HEALTH. Pryor, Lisa // Monthly: Australian Politics, Society & Culture;Jul2011, Issue 69, p32 

    An essay is presented on issues related to attenuated psychosis syndrome and its implications on adolescent mental health services in Australia. It discusses the Early Psychosis Prevention and Intervention Centre (EPPIC) and Headspace centre founded by professor Patrick McGorry and his research...

Share

Read the Article

Courtesy of VIRGINIA BEACH PUBLIC LIBRARY AND SYSTEM

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics