COMMENTARY: Oral decontamination with chlorhexidine reduced ventilator-associated pneumonia in high-risk patients

Ruest, Annie; Cook, Deborah
November 2006
ACP Journal Club;Nov/Dec2006, Vol. 145 Issue 3, p68
Academic Journal
The article focuses on a study on the effectiveness of prophylactic oral chlorhexidine to prevent ventilator-associated pneumonia (VAP) in high-risk patients. The study involved a placebo-controlled trial. In this trial, chlorhexidine with or without colistin was effective for reducing the daily risk for VAP. The study revealed that oral decontamination with chlorhexidine reduced VAP in patients and is an effective pneumonia prevention strategy in comparison to other prophylactic strategies.


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