Determination of metformin based on amplification of its voltammetric response by a combination of molecular wire and carbon nanotubes

Xin-juan Tian; Jun-feng Song; Xin-jun Luan; Yao-yu Wang; Qi-zhen Shi
December 2006
Analytical & Bioanalytical Chemistry;Dec2006, Vol. 386 Issue 7/8, p2081
Academic Journal
Molecular wires containing copper(II) (CuMW), in the form of the coordination polymer (Cu(II)4(bpp)4(maa)8(H2O)2).2H2O (bpp=1,3-bis(4-pyridyl)propane, maa=2-methylacrylic acid), and multiwalled carbon nanotubes (CNT) have been combined to prepare a paste electrode (CuMW/CNT/PE). The voltammetric response of the CuMW/CNT/PE to metformin (MET) was significantly greater than that of electrodes prepared from other materials, because of both the surface effect of CuMW and CNT and coordination of MET with the Cu(II) ion in the CuMW. A novel voltammetric method for determination of MET is proposed. In pH 7.2 Britton–Robinson buffer, using single sweep voltammetry, the second-order derivative peak current for oxidation of MET at 0.97 V (relative to SCE) increased linearly with MET concentration in the range 9.0 × 10−7–5.0 × 10−5 mol L−1 and the detection limit was 6.5 × 10−7 mol L−1. [Figure not available: see fulltext.]


Related Articles

  • Nanocables de cobre para células solares y pantallas fl exibles.  // DYNA - Ingeniería e Industria;feb2011, Vol. 86 Issue 1, p20 

    No abstract available.

  • Nano, nano.  // Machine Design;2/22/2007, Vol. 79 Issue 4, p66 

    The article focuses on the results of a study on the use of carbon nanotubes in conducting electricity, carried out by researchers at Rensselaer Polytechnic Institute in Troy, New York. The researchers concluded that carbon nanotubes conduct electricity much better than copper wires. With carbon...

  • Synthesis of carbon nanotubes with totally hollow channels and/or with totally copper filled nanowires. Zhang, Q.; Qian, W. Z.; Yu, H.; Wei, F.; Wen, Q. // Applied Physics A: Materials Science & Processing;Jan2006, Vol. 86 Issue 2, p265 

    Carbon nanotubes (CNTs) with totally hollow channels and/or totally filled copper nanowires have been fabricated by methane decomposition using copper microgrid as a catalyst at 1173 K. The formation mechanism of CNTs with totally hollow channels is carbon precipitation at carbon-metal interface...

  • Dispersion of carbon nanotubes in polymer matrix by in-situ emulsion polymerization. Zhang, W.; Yang, M.J. // Journal of Materials Science;Aug2004, Vol. 39 Issue 15, p4921 

    Reports a process to efficiently disperse carbon nanotubes (CNTs) in polyacrylic latex. Process involving in situ emulsion polymerization of acrylic monomers, including methyl methacrylate (MMA), butylacrylate (BA), methacrylic acid (MAA) and hydroxyethyl methacrylate (HEMA), with the presence...

  • Melamine selective electrode based on nanoporous carbon/molecularly imprinted polymer. Harsini, Muji; Suyanto; Pari, Gustan; Mandasari, Eva // Journal of Chemical & Pharmaceutical Research;2014, Vol. 6 Issue 9, p65 

    Potentiometric sensor of melamine based on nanoporous carbon/molecularly imprinted polymer (MIP) have been made and characterized. The purpose of research are to know the optimum conditions in the analysis of melamine and validation method. Molecularly Imprinted Polymer (MIP) is synthesized by...

  • Alignment of Nanoscale Single-Walled Carbon Nanotubes Strands. Danna Yang; Lin Wang; Xiaoxian Zhang; Dongwei Wang; Zhiqiang Shen; Sai Li // Nano-Micro Letters;2011, Vol. 3 Issue 3, p146 

    Depositing single-walled carbon nanotubes (SWNTs) with controllable density, pattern and orientation on electrodes presents a challenge in today's research. Here, we report a novel solvent evaporation method to align SWNTs in patterns having nanoscale width and micronscale length. SWNTs...

  • Young's Modulus of Nanowires Measured by Electrostatic Attraction: Application to Multi-Walled Carbon Nanotubes. Le Touze, Christophe; Hsiu-Lun Yeh; Chuen-Horng Tsai // Current Nanoscience;Jun2010, Vol. 6 Issue 3, p249 

    An electrostatic experiment, performed inside a Field-Emission Scanning Electron Microscope equipped with two electrical probes, is used for the accurate determination of the Young's modulus of as-grown nanowires. One electrode being in contact with the substrate and the other one at close...

  • Highly compliant transparent electrodes. Shian, Samuel; Diebold, Roger M.; McNamara, Alena; Clarke, David R. // Applied Physics Letters;8/6/2012, Vol. 101 Issue 6, p061101 

    Adaptive optical devices based on electric field induced deformation of dielectric elastomers require transparent and highly compliant electrodes to conform to large shape changes. Electrical, optical, and actuation properties of acrylic elastomer electrodes fabricated with single-walled carbon...

  • Carbon nanotubes send LEDs home. Manners, David // Electronics Weekly;3/28/2007, Issue 2281, p15 

    The article states that researchers at the U.S. Department of Energy's Oak Ridge National Laboratory, working with the University of Tennessee, are developing electrodes composed of carbon nanotubes and magnetic nanowires to enhance the light emission from polymer-based organic LEDs. Using...


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics