Urease induced calcium precipitation by Helicobacter species may initiate gallstone formation

Beizer, C.; Kusters, J. G.; Kuipers, E. J.; van Vliet, A. H. M.
November 2006
Gut;Nov2006, Vol. 55 Issue 11, p1678
Academic Journal
The article discusses the possibility of gallstone formation initiated through urease induced calcium precipitation by Helicobacter species. According to sources, Helicobacter species can colonize the mammalian gastrointestinal and hepatobiliary tract resulting in a chronic infection. It was found that murine infection with the enterohepatic Helicobacter species H bilis and H hepaticus accelerated the formation of cholesterol gallstones in mice fed with a lithogenic diet.


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