TITLE

Human Papillomavirus Prevalence in Women Who Have and Have Not Undergone Hysterectomies

AUTHOR(S)
Castle, Philip E.; Schiffman, Mark; Glass, Andrew G.; Rush, Brenda B.; Scott, David R.; Wacholder, Sholom; Dunn, Anne; Burk, Robert D.
PUB. DATE
December 2006
SOURCE
Journal of Infectious Diseases;12/15/2006, Vol. 194 Issue 12, p1702
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
We compared human papillomavirus (HPV) prevalence in an age-stratified random sample of women who have undergone a hysterectomy (WH) (np573) with the HPV prevalence in age-matched women with intact cervices (women who have not undergone a hysterectomy [WNH]) (np581) participating in a study at Kaiser Permanente in Portland, Oregon. Testing cervicovaginal lavage fluids for >40 HPV genotypes using an MY09/11 L1 consensus primer polymerase chain reaction method, we found no statistical differences in the prevalence of HPV (16% for WNH vs. 13.9% for WH) or carcinogenic HPV (6.5% for WNH vs. 4.5% for WH) between the 2 groups of women. Although WH have a similar prevalence of carcinogenic HPV infection, compared with WNH without a cervix, they have minimal risk of HPV-induced cancer and are unlikely to benefit from HPV testing.
ACCESSION #
23138241

 

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