TITLE

Anticoagulation in venous thrombosis

AUTHOR(S)
Schulman, Sam
PUB. DATE
November 1996
SOURCE
Journal of the Royal Society of Medicine;Nov1996, Vol. 89 Issue 11, p624
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Major studies addressing various aspects of the treatment of deep vein thrombosis are reviewed. It has lately been demonstrated that heparin should be dosed according to body weight and is preferably given as subcutaneous injections twice daily. Alternatively, low-molecular-weight heparins may be given in a fixed dose once daily, which does not require monitoring. Oral anticoagulation should be started concomitantly with heparin and targeted at an international normalized ratio of 2.0-3.0. This treatment should continue for a longer duration than previously accepted, in many cases for 6 months. For patients with contraindications to oral anticoagulation, secondary prophylaxis with a low-molecular-weight heparin is also effective and safe.
ACCESSION #
23082239

 

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