Angry breathing: A prospective study of hostility and lung function in the Normative Aging Study

Kubzansky, L. D.; Sparrow, D.; Jackson, B.; Cohen, S.; Weiss, S. I.; Wright, R. J.; Weiss, S T
October 2006
Thorax;Oct2006, Vol. 61 Issue 10, p863
Academic Journal
journal article
Background: Hostility and anger are risk factors for, or co-occur with, many health problems of older adults such as cardiovascular diseases, all-cause mortality, and asthma. Evidence that negative emotions are associated with chronic airways obstruction suggests a possible role for hostility in the maintenance and decline of pulmonary function. This study tests the hypothesis that hostility contributes to a faster rate of decline in lung function in older adults. Methods: A prospective examination was undertaken of the effect of hostility on change in lung function over time. Data are from the VA Normative Aging Study, an ongoing cohort of older men. Hostility was measured in 1986 in 670 men who also had an average of three pulmonary function examinations obtained over an average of 8.2 years of follow up. Hostility was ascertained using the 50-item MMPI based Cook-Medley Hostility Scale. Pulmonary function was assessed using spirometric tests to obtain measures of forced expiratory volume in 1 second (FEV1) and forced vital capacity (FVC). Results: Baseline pulmonary function differed between high and medium/low hostility groups (mean (SE) percent predicted FEV1 88.9 (18.5) v 95.3 (16.9) and FVC 92.5 (16.5) v 98.9 (15.9), respectively; p<0.01 for both). This overall association between higher hostility and reduced lung function remained significant after adjusting for smoking and education, although the effect size was attenuated for both FEV1 and FVC. Higher hostility was associated with a more rapid decline in lung function, and this effect was unchanged and remained significant for FEV1 in multivariate models but was attenuated for FVC. Each standard deviation increase in hostility was associated with a loss in FEV1 of approximately 9 mI/year. Conclusions: This study is one of the first to show prospectively that hostility is associated with poorer pulmonary function and more rapid rates of decline among older men.


Related Articles

  • Higher Lipoprotein (a) Levels Are Associated with Better Pulmonary Function in Community-Dwelling Older People – Data from the Berlin Aging Study II. Buchmann, Nikolaus; Kassner, Ursula; Norman, Kristina; Goldeck, David; Eckardt, Rahel; Pawelec, Graham; Steinhagen-Thiessen, Elisabeth; Demuth, Ilja // PLoS ONE;09/30/2015, Vol. 10 Issue 10, p1 

    Reduced pulmonary function and elevated serum cholesterol levels are recognized risk factors for cardiovascular disease. Currently, there is some controversy concerning relationships between cholesterol, LDL-cholesterol, HDL-cholesterol, serum triglycerides and lung function. However, most...

  • Famine in the Young and Risk of Later Hospitalization for COPD and Asthma. van Abeelen, Annet F. M.; Elias, Sjoerd G.; de Jong, Pim A.; Grobbee, Diederick E.; Bossuyt, Patrick M. M.; van der Schouw, Yvonne T.; Roseboom, Tessa J.; Uiterwaal, Cuno S. P. M. // PLoS ONE;Dec2013, Vol. 8 Issue 12, p1 

    Background: Undernutrition during critical periods of growth and development may permanently affect lung physiology and function. Objectives: To investigate whether acute undernutrition in childhood or young adulthood increases the risk of later hospitalization for obstructive airways disease,...

  • Effect of living close to a main road on asthma, allergy, lung function and chronic obstructive pulmonary disease. Pujades-Rodríguez, M.; Lewis, S.; Mckeever, T.; Britton, J.; Venn, A. // Occupational & Environmental Medicine;Oct2009, Vol. 66 Issue 10, p8 

    Background: A number of epidemiological studies suggest that the risk of asthma is increased among those living in close proximity to major roads. However, the evidence is inconsistent, and effects on asthma and related respiratory and allergic conditions using objective measures such as lung...

  • Respiratory Care Year in Review 2010: Part 1. Asthma, COPD, Pulmonary Function Testing, Ventilator-Associated Pneumonia. Rubin, Bruce K.; Dhand, Rajiv; Ruppel, Gregg L.; Branson, Richard D.; Hess, Dean R. // Respiratory Care;Apr2011, Vol. 56 Issue 4, p488 

    The purpose of this paper is to review the recent literature related to asthma, COPD, pulmonary function testing, and ventilator-associated pneumonia. Topics covered related to asthma include genetics and epigenetics; exposures; viruses; diet, obesity and exercise; exhaled nitric oxide; and drug...

  • Usefulness of peak expiratory flow measurements: is it just a matter of instrument accuracy? Brusasco, V. // Thorax;May2003, Vol. 58 Issue 5, p375 

    Editorial. Argues on the use of peak expiratory flow (PEF) as a main or sole measure of lung function, incorporated in the guidelines for diagnosis and management of asthma. Lack of usefulness of PEF in asthma monitoring; PEF measurements' possibility of detecting deterioration in airway...

  • COMPLICATED BRONCHIAL ASTHMA.  // Cortlandt Forum;06/25/2001, Vol. 14 Issue 6, p83 

    Answers queries on complicated bronchial asthma of patients with restrictive component on pulmonary function testing in Lorain County, Ohio. Causes of the asthma; Determination on the relation between obstructive and restrictive components; Evaluation of lung disease.

  • Tiotropium vs. Salmeterol in the Treatment of COPD. Miller, Karl E. // American Family Physician;12/1/2002, Vol. 66 Issue 11, p2155 

    Discusses the study 'A 6-month, placebo-controlled study comparing lung function and health status changes in COPD patient treated with tiotropium or salmeterol,' by J.F. Donohue et al., from the July 2002 issue of 'Chest.'

  • HEALTH WATCH.  // Yoga Journal;Mar/Apr2004, Issue 180, p32 

    Presents health-related news items, as of March 2004. Tendency of people who experience a great deal of hostility and impatience to develop hypertension; Benefit for overweight postmenopausal women of stretching and exercise upon waking; Health care expenses of backache patients.

  • ALLERGEN EXPOSURE AND THE DEVELOPMENT OF ASTHMA. Sporik, R.; Platts-Mills, T. A. E. // Thorax;Sep2001 Supp, Vol. 56, pii58 

    Background: In a prospective birth cohort study, we assessed the relevance of mite and cat allergen exposure for the development of childhood asthma up to age 7 years. Methods: Of 1314 newborn infants enrolled in five German cities in 1990, follow-up data at age 7 years were available for 939...


Read the Article


Sign out of this library

Other Topics