TITLE

Detection of bacteria by surface-enhanced Raman spectroscopy

AUTHOR(S)
Sengupta, Atanu; Mujacic, Mirna; Davis, E. James
PUB. DATE
December 2006
SOURCE
Analytical & Bioanalytical Chemistry;Dec2006, Vol. 386 Issue 5, p1379
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
The detection and identification of dilute bacterial samples by surface-enhanced Raman spectroscopy has been explored by mixing aqueous suspensions of bacteria with a suspension of nanocolloidal silver particles. An estimate of the detection limit of E. coli was obtained by varying the concentration of bacteria. By correcting the Raman spectra for the broad librational OH band of water, reproducible spectra were obtained for E. coli concentrations as low as approximately 103 cfu/mL. To aid in the assignment of Raman bands, spectra for E. coli in D2O are also reported. [Figure not available: see fulltext.]
ACCESSION #
22897029

 

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