Determination of cadmium in oyster tissue using isotope dilution inductively coupled plasma mass spectrometry: comparison of results obtained in the standard and He/H2 cell modes

Yip, Yiu-chung; Chu, Hei-shing; Chan, Kwok-chu; Chan, Kam-kit; Cheung, Ping-yuk; Sham, Wing-cheong
December 2006
Analytical & Bioanalytical Chemistry;Dec2006, Vol. 386 Issue 5, p1475
Academic Journal
An inductively coupled plasma quadrupole mass spectrometer equipped with an octopole collision/reaction cell was used for the determination of cadmium in oyster tissue samples using isotope dilution inductively coupled plasma mass spectrometry. The oyster samples in question were found to contain Mo and Zr. In our feasibility study on a Cd standard solution (10 μg L−1) containing a matrix of Mo (1000 μg L−1) or Zr (250 μg L−1), the potentially interfering species (MoO+ or ZrO+) present at the analytical mass of cadmium concerned ( m/ z 111, 112 or 114) was reduced effectively through the use of a mixture of He and H2 as cell gases. The accuracy of the method was validated by the analysis of a matrix-matched certified reference material (CRM) of NIST SRM 1566b. The CRM was analyzed under the standard and He/H2 cell modes. Two isotopic pairs of 114Cd/111Cd and 112Cd/111Cd were selected for quantification purposes. The recoveries of cadmium obtained in the two cell modes were compared with each other. The validated method was applied successfully to the APMP.QM-P5 pilot study for international comparability purposes.


Related Articles

  • Determination of cadmium in grains by isotope dilution ICP—MS and coprecipitation using sample constituents as carrier precipitants. Inagaki, Kazumi; Narukawa, Tomohiro; Yarita, Takashi; Takatsu, Akiko; Okamoto, Kensaku; Chiba, Koichi // Analytical & Bioanalytical Chemistry;Oct2007, Vol. 389 Issue 3, p691 

    A coprecipitation method using sample constituents as carrier precipitants was developed that can remove molybdenum, which interferes with the determination of cadmium in grain samples via isotope dilution inductively coupled plasma mass spectrometry (ID-ICPMS). Samples were digested with HNO3,...

  • Isotope dilution analysis for speciation. Ruiz Encinar, Jorge // Analytical & Bioanalytical Chemistry;Jan2003, Vol. 375 Issue 1, p41 

    The article presents information about isotope dilution analysis for speciation. The use of compounds isotopic ally labelled with D and/or 13C has been widespread in organic chemistry during the last 25 years but it was only few years ago, coinciding with the inductively coupled plasma mass...

  • The role of sulfur and sulfur isotope dilution analysis in quantitative protein analysis. Rappel, Christina; Schaumlöffel, Dirk // Analytical & Bioanalytical Chemistry;Jan2008, Vol. 390 Issue 2, p605 

    The element sulfur is almost omnipresent in all natural proteomes and plays a key role in protein quantification. Incorporated in the amino acids cysteine and methionine, it has been served as target for many protein-labeling reactions in classic quantitative proteomic approaches based on...

  • Ultratrace-level radium-226 determination in seawater samples by isotope dilution inductively coupled plasma mass spectrometry. Varga, Zsolt // Analytical & Bioanalytical Chemistry;Jan2008, Vol. 390 Issue 2, p511 

    An improved and novel sample preparation method for 226Ra determination in liquid samples by isotope dilution inductively coupled plasma sector field mass spectrometry using laboratory-prepared 228Ra tracer has been developed. The procedure involves a selective preconcentration achieved by...

  • Development of a species-specific isotope dilution GC-ICP-MS method for the determination of thiophene derivates in petroleum products. Heilmann, Jens; Heumann, Klaus G. // Analytical & Bioanalytical Chemistry;Jan2008, Vol. 390 Issue 2, p643 

    A species-specific isotope dilution technique for accurate determination of sulfur species in low- and high-boiling petroleum products was developed by coupling capillary gas chromatography with quadrupole ICP-MS (GC-ICP-IDMS). For the isotope dilution step 34S-labeled thiophene,...

  • On-line species-unspecific isotope dilution analysis in the picomolar range reveals the time- and species-depending mercury uptake in human astrocytes. Wehe, Christoph; Pieper, Imke; Holtkamp, Michael; Thyssen, Georgina; Sperling, Michael; Schwerdtle, Tanja; Karst, Uwe // Analytical & Bioanalytical Chemistry;Mar2014, Vol. 406 Issue 7, p1909 

    In order to reveal the time-depending mercury species uptake by human astrocytes, a novel approach for total mercury analysis is presented, which uses an accelerated sample introduction system combined on-line with an inductively coupled plasma mass spectrometer equipped with a...

  • Isotopic analyses by ICP-MS in clinical samples. Rodushkin, Ilia; Engström, Emma; Baxter, Douglas // Analytical & Bioanalytical Chemistry;Mar2013, Vol. 405 Issue 9, p2785 

    This critical review focuses on inductively coupled plasma mass spectrometry (ICP-MS) based applications for isotope abundance ratio measurements in various clinical samples relevant to monitoring occupational or environmental exposure, human provenancing and reconstruction of migration pathways...

  • Mercury speciation analysis in human hair by species-specific isotope-dilution using GC-ICP-MS. Laffont, Laure; Maurice, Laurence; Amouroux, David; Navarro, Patricia; Monperrus, Mathilde; Sonke, Jeroen; Behra, Philippe // Analytical & Bioanalytical Chemistry;Mar2013, Vol. 405 Issue 9, p3001 

    We optimized a mercury (Hg) speciation extraction method for human hair in combination with species-specific isotope-dilution analysis by gas chromatography-inductively coupled plasma-mass spectrometry (GC-ICP-MS). The method was validated on human hair reference material RM (IAEA-086), which is...

  • Quantification of Fe atoms by MC-ICP-MS for the redetermination of the half-life. Kivel, Niko; Schumann, Dorothea; Günther-Leopold, Ines // Analytical & Bioanalytical Chemistry;Mar2013, Vol. 405 Issue 9, p2965 

    In many scientific fields, the half-life of radionuclides plays an important role. The accurate knowledge of this parameter has direct impact on, e.g., age determination of archeological artifacts and of the elemental synthesis in the universe. In order to derive the half-life of a long-lived...


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics