Pharmacological appraisal of fixed-dose combination medicines: discussion paper

Snell, Eric S.
June 1982
Journal of the Royal Society of Medicine;Jun1982, Vol. 75 Issue 6, p457
Academic Journal
The article discuses on the combination medicines over to single products and over multiple drug regimes in Great Britain. The alleged disadvantages of the products are mostly of theoretical or doctrinal. Nearly all medicines are formulated mixture of several chemicals and a single active ingredients may be metabolized to a variety of substances with different therapeutic and toxic effects. Discrimination against combination medicine is on pharmacological grounds is questionable.


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