TITLE

Axillary Regional Recurrence After Sentinel Lymph Node Biopsy for Breast Cancer

AUTHOR(S)
Rosing, David K.; Dauphine, Christine E.; Vargas, M. Perla; Gonzalez, Katherine; Burla, Melissa; Kaufmann, Paul; Vargas, Hernan I.
PUB. DATE
October 2006
SOURCE
American Surgeon;Oct2006, Vol. 72 Issue 10, p939
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
The accuracy of sentinel lymph node biopsy (SLNB) staging in breast cancer has been demonstrated in studies comparing it with axillary dissection. There is a 5 per cent false-negative rate, but this does not always correlate with axillary recurrence. Our purpose was to determine the rate of axillary lymphatic recurrence in breast cancer patients who had a negative SLNB. We conducted a cohort study of breast cancer patients who underwent SLNB between 2001 and 2005. Only patients who had a negative SLNB were included. Patient demographics and tumor factors were reviewed. Outcomes measured were axillary and systemic recurrence and survival. Eighty-nine patients with a mean age of 54.4 ± 9.9 years were included. Eighty-nine per cent of cases had infiltrating ductal carcinoma histology. Mean tumor size was 19 ± 14 mm. Breast conservation surgery was done in 65 cases and mastectomy in 24. A mean of 2.3 ± 2.4 SLN were found. After a median follow-up of 2.15 years, 1 (1%) patient developed a lymphatic recurrence in the axilla. SLNB provides accurate staging of breast cancer. Patients with negative SLNB do not require axillary dissection.
ACCESSION #
22667480

 

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