Drinking from the fountain of promise: biomarkers in the surveillance of Barrett's oesophagus—the glass is half full!

Preston, S. L.; Jankowski, J. A.
October 2006
Gut;Oct2006, Vol. 55 Issue 10, p1377
Academic Journal
The article comments on the usefulness of biomarkers in the study of Barrett's esophagus. Barrett's esophagus is an acquired premalignant condition that is a precursor to esophageal adenocarcinoma. One biomarker method being described is the utilization of p53 immunostaining in esophageal biopsies. The researchers discovered that biomarker levels are higher in adenomatous than the metaplastic Barrett's esophagus tissue.


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