TITLE

Primary Hepatic Lymphoma in Hepatitis C: Case Report and Review of the Literature

AUTHOR(S)
Chowla, Arun; Malhi-Chowla, Navreet
PUB. DATE
September 1999
SOURCE
American Surgeon;Sep1999, Vol. 65 Issue 9, p881
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Primary B-cell lymphoma of the liver is an extremely rare tumor. The higher incidence of hepatocellular carcinoma in hepatitis C is well known, but the relationship with lymphoma is unclear. An increased incidence has been reported in patients with chronic hepatitis C. Hepatitis C virus is known to be a lymphotropic virus. Mixed cryoglobulinemia, which is a benign lymphoproliferative disorder, has a definite association with hepatitis C. It is postulated that the virus may also induce a malignant transformation. We describe an unusual presentation of a case of asymptomatic left hepatic mass in a patient with hepatitis C with a preoperative diagnosis of hepatocellular carcinoma. He underwent a left lateral segmentectomy, and the pathologic examination revealed non-Hodgkin's lymphoma. The clinical features, radiologic investigations, and pathologic findings are presented. A review of the literature discussing clinical features, postulated pathogenetic mechanisms, and management options is also presented.
ACCESSION #
2258995

 

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