Review: Ribavirin is not better than placebo in chronic hepatitis C infection

September 2006
ACP Journal Club;Sep/Oct2006, Vol. 145 Issue 2, p47
Academic Journal
The article focuses on studies which examine whether ribavirin monotherapy is more effective than placebo in patients with chronic hepatitis C infection, or whether no intervention is required. Assessment of individual studies was based on randomization, allocation concealment, and blinding. It was seen that loss of hepatitis C virus RNA months after treatment and a composite endpoint of liver-related morbidity or all, cause mortality. Ribavirin monotherapy is not better than placebo.


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